Regulatory circuitry governing fungal development, drug resistance, and disease

RS Shapiro, N Robbins, LE Cowen - Microbiology and molecular …, 2011 - Am Soc Microbiol
Pathogenic fungi have become a leading cause of human mortality due to the increasing
frequency of fungal infections in immunocompromised populations and the limited …

Expanding fungal pathogenesis: Cryptococcus breaks out of the opportunistic box

JW Kronstad, R Attarian, B Cadieux, J Choi… - Nature reviews …, 2011 - nature.com
Cryptococcus neoformans is generally considered to be an opportunistic fungal pathogen
because of its tendency to infect immunocompromised individuals, particularly those …

[HTML][HTML] Mitigating amphibian disease: strategies to maintain wild populations and control chytridiomycosis

DC Woodhams, J Bosch, CJ Briggs, S Cashins… - Frontiers in …, 2011 - Springer
Background Rescuing amphibian diversity is an achievable conservation challenge.
Disease mitigation is one essential component of population management. Here we assess …

Mucormycosis: its contemporary face and management strategies

HY Sun, N Singh - The Lancet infectious diseases, 2011 - thelancet.com
Several countries have seen rising frequencies of mucormycosis among patients with
haematological disorders, malignancies, or diabetes mellitus, and among transplant …

Incipient and subclinical tuberculosis: defining early disease states in the context of host immune response

JM Achkar, ER Jenny-Avital - Journal of Infectious Diseases, 2011 - academic.oup.com
Latent Mycobacterium tuberculosis infection (LTBI) and active tuberculosis (TB) are 2 ends
of a spectrum of states ranging from asymptomatic infection to overt disease. While …

Coevolution of TH1, TH2, and TH17 Responses during Repeated Pulmonary Exposure to Aspergillus fumigatus Conidia

BJ Murdock, AB Shreiner, RA McDonald… - Infection and …, 2011 - Am Soc Microbiol
Aspergillus fumigatus, a ubiquitous airborne fungus, can cause invasive infection in
immunocompromised individuals but also triggers allergic bronchopulmonary aspergillosis …

[HTML][HTML] Pathogen-derived effectors trigger protective immunity via activation of the Rac2 enzyme and the IMD or Rip kinase signaling pathway

L Boyer, L Magoc, S Dejardin, M Cappillino… - Immunity, 2011 - cell.com
Although infections with virulent pathogens often induce a strong inflammatory reaction,
what drives the increased immune response to pathogens compared to nonpathogenic …

Non-tuberculous mycobacterium infection after lung transplantation is associated with increased mortality

HC Huang, SS Weigt, A Derhovanessian… - The Journal of heart and …, 2011 - Elsevier
Background Pulmonary non-tuberculous mycobacterial (NTM) infection is relatively common
after lung transplantation, but the effect on mortality remains undetermined. Herein we …

Opportunistic infection-associated immune reconstitution syndrome in transplant recipients

HY Sun, N Singh - Clinical infectious diseases, 2011 - academic.oup.com
Reversal of pathogen-induced immunosuppression upon employment of effective
antimicrobial therapy and withdrawal of iatrogenic immunosuppression has the potential to …

Amoeba provide insight into the origin of virulence in pathogenic fungi

A Casadevall - Recent advances on model hosts, 2011 - Springer
Why are some fungi pathogenic while the majority poses no threat to humans or other
hosts? Of the more than 1.5 million fungal species only about 150–300 are pathogenic for …