Repeated exposure to drugs of abuse enhances the motor-stimulant response to these
drugs, a phenomenon termed behavioral sensitization. Animals that are extinguished from …

The repeated use of drugs that directly or indirectly stimulate dopamine transmission carry
addiction liability and produce enduring pathological changes in the brain circuitry that …

In this review, we highlight the role of neuroimaging techniques in studying the emotional
and cognitive-behavioral components of the addiction syndrome by focusing on the neural …

It is well established that acute morphine withdrawal can be observed following opioid
receptor antagonism in rodents. Glutamate receptor antagonists can attenuate the …

Topiramate is one of the currently most promising compounds in the field of addiction
medicine. This paper discusses its potential utility related to a phase model of addiction …

Substance addiction is a chronically relapsing disorder that has been characterized by a
vicious cycle composed of intoxication, craving/anticipation, withdrawal, and response …

Substance addiction is a chronically relapsing disorder that has been characterized by a
vicious cycle composed of intoxication, craving/anticipation, withdrawal, and response …

Cocaine use and abuse remains a major public health issue characterized by relapse to
drug seeking and taking following periods of abstinence. This dissertation sought to …