Sympathetic mechanisms, organ damage, and antihypertensive treatment

G Grassi, G Seravalle, R Dell'Oro, G Mancia - Current hypertension …, 2011 - Springer
Sympathetic activation characterizes essential hypertension, contributing to the
development and progression of the high blood pressure state. Throughout the years …

Relationships of adrenoceptor polymorphisms with obesity

K Masuo, GW Lambert - Journal of Obesity, 2011 - Wiley Online Library
Obesity, hypertension, and type 2 diabetes are rapidly growing public health problems.
Heightened sympathetic nerve activity is a well‐established observation in obesity …

Sympathetic and parasympathetic activity in cancer-related fatigue: more evidence for a physiological substrate in cancer survivors

CP Fagundes, DM Murray, BS Hwang, JP Gouin… - …, 2011 - Elsevier
Fatigue is a notable clinical problem in cancer survivors, and understanding its
pathophysiology is important. This study evaluated relationships between fatigue and both …

Inflammatory cytokines in paraventricular nucleus modulate sympathetic activity and cardiac sympathetic afferent reflex in rats

Z Shi, XB Gan, ZD Fan, F Zhang, YB Zhou… - Acta …, 2011 - Wiley Online Library
Aim: This study was to determine the roles of inflammatory cytokines in paraventricular
nucleus (PVN) in modulating sympathetic activity, blood pressure and cardiac sympathetic …

Effects on blood pressure and autonomic nervous system function of a 12‐week exercise or exercise plus DASH‐diet intervention in individuals with elevated blood …

KM Edwards, KL Wilson, J Sadja, MG Ziegler… - Acta …, 2011 - Wiley Online Library
Aim: Hypertension is related to abnormalities in autonomic nervous system (ANS) function,
with increased sympathetic output and decreased parasympathetic tone. Lifestyle …

Skeletal muscle reflex-mediated changes in sympathetic nerve activity are abnormal in spontaneously hypertensive rats

M Mizuno, MN Murphy, JH Mitchell… - American Journal of …, 2011 - journals.physiology.org
In hypertension, the blood pressure response to exercise is exaggerated. We demonstrated
previously that this heightened pressor response to physical activity is mediated by an …

Interactions between sympathetic nervous system and endogenous endothelin in patients with essential hypertension

RM Bruno, I Sudano, L Ghiadoni, L Masi, S Taddei - Hypertension, 2011 - Am Heart Assoc
Experimental evidence indicates that endothelin 1 stimulates the sympathetic nervous
system by activation of the subtype A receptor. The aim of the present study was to assess …

Angiotensin AT1 receptors in paraventricular nucleus contribute to sympathetic activation and enhanced cardiac sympathetic afferent reflex in renovascular …

AD Chen, SJ Zhang, N Yuan, Y Xu, W De… - Experimental …, 2011 - Wiley Online Library
Sympathetic activity is enhanced in hypertension, which contributes to the pathogenesis of
hypertension and progression of organ damage. The cardiac sympathetic afferent reflex …

Renal denervation: potential impact on hypertension in kidney disease?

PJ Blankestijn, E Ritz - Nephrology Dialysis Transplantation, 2011 - academic.oup.com
About a year ago, the introduction of catheter-based renal denervation was briefly
mentioned in an editorial in Nephrology Dialysis Transplantation [1]. In view of recent new …

Protein kinase CK2 increases glutamatergic input in the hypothalamus and sympathetic vasomotor tone in hypertension

ZY Ye, DP Li, L Li, HL Pan - Journal of Neuroscience, 2011 - Soc Neuroscience
Increased glutamatergic input in the paraventricular nucleus (PVN) is important for high
sympathetic outflow in hypertension, but the associated molecular mechanisms remain …