TDM-guided therapy with daptomycin and meropenem in a morbidly obese, critically ill patient

F Pea, P Cojutti, R Sbrojavacca… - Annals of …, 2011 - journals.sagepub.com
Objective: To describe a case of severe cellulitis, successfully treated with high-dose
daptomycin plus continuous infusion meropenem, in a patient with morbid obesity and renal …

Year in review 2010: Critical Care- infection

L Pagani, A Afshari, S Harbarth - Critical care, 2011 - Springer
Infections remain among the most important concerns in critically ill patients. Early and
reliable diagnosis of infection still poses difficulties in this setting but also represents a …

Pharmacodynamic profiling of intravenous antibiotics against prevalent Gram-negative organisms across the globe: the Passport Program—Asia-Pacific Region

JA Roberts, A Kwa, P Montakantikul… - International journal of …, 2011 - Elsevier
Due to escalating antimicrobial resistance amongst Gram-negative organisms, the choice of
effective empirical antimicrobial regimens has become challenging. Monte Carlo simulations …

Optimizing antibiotic pharmacodynamics in hospital-acquired and ventilator-acquired bacterial pneumonia

ST Housman, JL Kuti… - Clinics in Chest …, 2011 - chestmed.theclinics.com
Nosocomial pneumonia, the second most common type of hospital-acquired infection in the
United States, can be further classified by when and where it was acquired. 1–3 The …

Pharmacodynamic Profiling of Antimicrobials against Gram‐negative Respiratory Isolates from Canadian Hospitals

RA Keel, GG Zhanel, S Zelenitsky… - Canadian Journal of …, 2011 - Wiley Online Library
The objective of this study was to assess the profile of a variety of dosing regimens for
common intravenous antibiotics against contemporary Enterobacter cloacae, Escherichia …