Oral self-emulsifying drug delivery systems, from biopharmaceutical to technical formulation aspects

M Kuentz - Journal of Drug Delivery Science and Technology, 2011 - Elsevier
Self-emulsifying drug delivery systems can include a broad range of oils, surfactants and co-
solvents. A spontaneous fine emulsion or micro-emulsion is formed in contact with water or …

The conflict between in vitro release studies in human biorelevant media and the in vivo exposure in rats of the lipophilic compound fenofibrate

TT Do, M Van Speybroeck, R Mols, P Annaert… - International journal of …, 2011 - Elsevier
The performance of four different lipid-based (Tween 80–Captex 200P, Tween 80–Capmul
MCM, Tween 80–Caprol 3GO and Tween 80–soybean oil) and one commercially available …

In situ formation of nanocrystals from a self-microemulsifying drug delivery system to enhance oral bioavailability of fenofibrate

YM Lin, JY Wu, YC Chen, YD Su, WT Ke… - International Journal …, 2011 - Taylor & Francis
Objectives In situ formation of nanocrystals and dissolution profiles of fenofibrate (FFB) from
a self-microemulsifying drug delivery system (SMEDDS) were characterized. Methods …

[PDF][PDF] Preparation and evaluation of self-microemulsifying drug delivery system of carvedilol

MRP Rao, GS Munjapara, IA Khole - Latin Am J Pharm, 2011 - researchgate.net
The objective of the work was to develop, optimize and evaluate self-microemulsifying drug
delivery system (SMEDDS) of carvedilol (CDL), a poorly water-soluble drug. SMEDDS was …

[PDF][PDF] Improvement of oral bioavailability of nifedipine through self-microemulsifing drug delivery systems

MS Kumar, P Shailaja, KR MURTHY… - J. Glob. Trends Pharm …, 2011 - jgtps.com
Self-microemulsifying drug delivery systems (SMEDDS) of nifedipine were prepared,
characterized and subjected for in-vitro and in-vivo evaluation. Pseudo-ternary phase …

Cutaneous composition comprising vitamin d analogue and a mixture of solvent and surfactants

K Petersson - 2011 - Google Patents
WO2011076207A2 - Cutaneous composition comprising vitamin d analogue and a mixture of
solvent and surfactants - Google Patents WO2011076207A2 - Cutaneous composition comprising …

Targeted Nanoparticle Subpopulation: Comparison with Self-Nanoemulsifying Drug-Delivery Systems in Pharmaceutical Research

J D'Arrigo - Studies in Interface Science, 2011 - Elsevier
The Filmix® nanoemulsion (including its self-assembling mixed-lipid nanoparticle
subpopulations) is easily produced using a relatively mild dispersing technique. The small …

Further Chemotherapy with Lipid Nanoemulsions: Targeting Certain Hyperproliferative Diseases, as well as Neoplasias, via “Lipoprotein Receptor”-Mediated …

J D'Arrigo - Studies in Interface Science, 2011 - Elsevier
Besides tumors, some other (noncancerous) lesion/injury sites involving hyperproliferative
disease processes (such as atherosclerosis as well as traumatic neuroinjury sites) often …

[PDF][PDF] Formulation of self-nanoemulsifying drug delivery systems containing

T Tran, T Rades, A Müllertz - Adv Drug Deliv Rev, 2011 - pharmaexcipients.com
The development of self-nanoemulsifying drug delivery systems (SNEDDS) to enhance the
oral bioavailability of lipophilic drugs, is usually based on traditional one-factor-at-a-time …

[引用][C] International Journal of Pharmaceutical Innovation Formulation and Evaluation of Self microemulsifying drug delivery systems of low solubility drug for …

D Bora, P Borude, K Bhise