Psychological stress in childhood and susceptibility to the chronic diseases of aging: moving toward a model of behavioral and biological mechanisms.
Among people exposed to major psychological stressors in early life, there are elevated
rates of morbidity and mortality from chronic diseases of aging. The most compelling data …
rates of morbidity and mortality from chronic diseases of aging. The most compelling data …
Epigenetic modifications: basic mechanisms and role in cardiovascular disease
DE Handy, R Castro, J Loscalzo - Circulation, 2011 - Am Heart Assoc
The term epigenetics was first used to refer to the complex interactions between the genome
and the environment that are involved in development and differentiation in higher …
and the environment that are involved in development and differentiation in higher …
The human connectome: a complex network
O Sporns - Annals of the new York Academy of Sciences, 2011 - Wiley Online Library
The human brain is a complex network. An important first step toward understanding the
function of such a network is to map its elements and connections, to create a …
function of such a network is to map its elements and connections, to create a …
Epigenetic predictor of age
S Bocklandt, W Lin, ME Sehl, FJ Sánchez… - PloS one, 2011 - journals.plos.org
From the moment of conception, we begin to age. A decay of cellular structures, gene
regulation, and DNA sequence ages cells and organisms. DNA methylation patterns change …
regulation, and DNA sequence ages cells and organisms. DNA methylation patterns change …
Transcriptional and epigenetic mechanisms of addiction
AJ Robison, EJ Nestler - Nature reviews neuroscience, 2011 - nature.com
Investigations of long-term changes in brain structure and function that accompany chronic
exposure to drugs of abuse suggest that alterations in gene regulation contribute …
exposure to drugs of abuse suggest that alterations in gene regulation contribute …
Folic acid food fortification—its history, effect, concerns, and future directions
KS Crider, LB Bailey, RJ Berry - Nutrients, 2011 - mdpi.com
Periconceptional intake of folic acid is known to reduce a woman's risk of having an infant
affected by a neural tube birth defect (NTD). National programs to mandate fortification of …
affected by a neural tube birth defect (NTD). National programs to mandate fortification of …
Child health, developmental plasticity, and epigenetic programming
Plasticity in developmental programming has evolved in order to provide the best chances of
survival and reproductive success to the organism under changing environments …
survival and reproductive success to the organism under changing environments …
Epigenome-wide association studies for common human diseases
VK Rakyan, TA Down, DJ Balding, S Beck - Nature Reviews Genetics, 2011 - nature.com
Despite the success of genome-wide association studies (GWASs) in identifying loci
associated with common diseases, a substantial proportion of the causality remains …
associated with common diseases, a substantial proportion of the causality remains …
Natural immunity: biodiversity loss and inflammatory diseases are two global megatrends that might be related
L Von Hertzen, I Hanski, T Haahtela - EMBO reports, 2011 - embopress.org
Natural immunity: Biodiversity loss and inflammatory diseases are two global megatrends that
might be related: EMBO reports: Vol 12, No 11 Skip to Article Content Skip to Article Information …
might be related: EMBO reports: Vol 12, No 11 Skip to Article Content Skip to Article Information …
Epigenetics and the origins of paternal effects
Though there are multiple routes through which parents can influence their offspring, recent
studies of environmentally induced epigenetic variation have highlighted the role of non …
studies of environmentally induced epigenetic variation have highlighted the role of non …