The HUman MicroNucleus project on eXfoLiated buccal cells (HUMNXL): The role of life-style, host factors, occupational exposures, health status, and assay protocol
The human buccal micronucleus cytome assay (BMCyt) is one of the most widely used
techniques to measure genetic damage in human population studies. Reducing protocol …
techniques to measure genetic damage in human population studies. Reducing protocol …
The effect of age, gender, diet and lifestyle on DNA damage measured using micronucleus frequency in human peripheral blood lymphocytes
Micronucleus (MN) frequency in cytokinesis-blocked peripheral blood lymphocytes (PBL)
has become one of the best-established biomarkers for studying DNA damage occurring in …
has become one of the best-established biomarkers for studying DNA damage occurring in …
The micronucleus assay as a biological dosimeter of in vivo ionising radiation exposure
Biological dosimetry, based on the analysis of micronuclei (MN) in the cytokinesis-block
micronucleus (CBMN) assay can be used as an alternative method for scoring dicentric …
micronucleus (CBMN) assay can be used as an alternative method for scoring dicentric …
The in vitro MN assay in 2011: origin and fate, biological significance, protocols, high throughput methodologies and toxicological relevance
M Kirsch-Volders, G Plas, A Elhajouji… - Archives of …, 2011 - Springer
Micronuclei (MN) are small, extranuclear bodies that arise in dividing cells from acentric
chromosome/chromatid fragments or whole chromosomes/chromatids lagging behind in …
chromosome/chromatid fragments or whole chromosomes/chromatids lagging behind in …
The HUMN and HUMNxL international collaboration projects on human micronucleus assays in lymphocytes and buccal cells—past, present and future
Abstract The International Human Micronucleus (HUMN) Project (www. humn. org) was
founded in 1997 to coordinate worldwide research efforts aimed at using micronucleus (MN) …
founded in 1997 to coordinate worldwide research efforts aimed at using micronucleus (MN) …
Problems and challenges in the development and validation of human cell-based assays to determine nanoparticle-induced immunomodulatory effects
Background With the increasing use of nanomaterials, the need for methods and assays to
examine their immunosafety is becoming urgent, in particular for nanomaterials that are …
examine their immunosafety is becoming urgent, in particular for nanomaterials that are …
Micronuclei in neonates and children: effects of environmental, genetic, demographic and disease variables
N Holland, A Fucic, DF Merlo, R Sram… - …, 2011 - academic.oup.com
Children may be more susceptible to the effects of the environmental exposure and medical
treatments than adults; however, limited information is available about the differences in …
treatments than adults; however, limited information is available about the differences in …
Genotoxicity biomarkers in occupational exposure to formaldehyde—the case of histopathology laboratories
Formaldehyde, classified by the IARC as carcinogenic in humans and experimental animals,
is a chemical agent that is widely used in histopathology laboratories. The exposure to this …
is a chemical agent that is widely used in histopathology laboratories. The exposure to this …
Automated scoring of lymphocyte micronuclei by the MetaSystems Metafer image cytometry system and its application in studies of human mutagen sensitivity and …
A Rossnerova, M Spatova, C Schunck, RJ Sram - Mutagenesis, 2011 - academic.oup.com
Automated image analysis scoring of micronuclei (MN) in cells can facilitate the objective
and rapid measurement of genetic damage in mammalian and human cells. This approach …
and rapid measurement of genetic damage in mammalian and human cells. This approach …
Automated image analysis of micronuclei by IMSTAR for biomonitoring
I Decordier, A Papine, K Vande Loock, G Plas… - …, 2011 - academic.oup.com
For many years, the analysis of micronuclei (MN) has been successfully applied to human
biomonitoring of in vivo genotoxin exposure and provides a sensitive and relatively easy …
biomonitoring of in vivo genotoxin exposure and provides a sensitive and relatively easy …