Asymmetric Synthesis of 1,2,9,9a-Tetrahydrocyclopropa[c]benzo[e]indol-4-one (CBI)

JP Lajiness, DL Boger - The Journal of organic chemistry, 2011 - ACS Publications
A short, asymmetric synthesis of the 1, 2, 9, 9a-tetrahydrocyclopropa [c] benzo [e] indol-4-
one (CBI) analogue of the CC-1065 and duocarmycin DNA alkylation subunits is described …

A new enantioselective approach to the core structure of hypoxia selective prodrugs related to the duocarmycins

DM Heinrich, JJ Youte, WA Denny, M Tercel - Tetrahedron letters, 2011 - Elsevier
The indoline scaffold of hypoxia selective prodrugs of DNA-alkylating agents related to the
duocarmycin natural products was synthesized via an enantioselective Friedel–Crafts …

New Methods for Heterocycle Preparation

JP Maciejewski - 2011 - d-scholarship.pitt.edu
This dissertation will describe the development and application of novel methods for
heterocycle preparation. The first chapter will outline the development of a titanocene …