Similarities in hypothalamic and mesocorticolimbic circuits regulating the overconsumption of food and alcohol

JR Barson, I Morganstern, SF Leibowitz - Physiology & behavior, 2011 - Elsevier
Historically, studies of food intake regulation started with the hypothalamus and gradually
expanded to mesocorticolimbic regions, while studies of drug use began with …

Regulation of drug and palatable food overconsumption by similar peptide systems

I Morganstern, JR Barson… - Current drug abuse …, 2011 - ingentaconnect.com
This review is aimed at understanding some of the common neurochemical, behavioral and
physiological determinants of drug and food overconsumption. Much current work has been …

Beneficial effect of galanin on insulin sensitivity in muscle of type 2 diabetic rats

B He, M Shi, L Zhang, G Li, L Zhang, H Shao, J Li… - Physiology & …, 2011 - Elsevier
The aim of this study was to determine whether enhanced galanin (GAL) release induced by
exercise would elevate insulin sensitivity and glucose transporter 4 (GLUT4) concentration …

Galanin antagonist increases insulin resistance by reducing glucose transporter 4 effect in adipocytes of rats

L Guo, M Shi, L Zhang, G Li, L Zhang, H Shao… - General and …, 2011 - Elsevier
Seeing that galanin increases animal body weight on the conditions of inhibiting insulin
secretion and animals with metabolic disorder of galanin easily suffer from diabetes, we …

Differential activity by polymorphic variants of a remote enhancer that supports galanin expression in the hypothalamus and amygdala: implications for obesity …

S Davidson, M Lear, L Shanley, B Hing… - …, 2011 - nature.com
The expression of the galanin gene (GAL) in the paraventricular nucleus (PVN) and in the
amygdala of higher vertebrates suggests the requirement for highly conserved, but …

Novel galanin receptor subtype specific ligands in feeding regulation

I Saar, J Runesson, I McNamara, J Järv… - Neurochemistry …, 2011 - Elsevier
Galanin a 29/30-residue neuropeptide has been implicated in several functions in the
central nervous system, including the regulation of food consumption. Galanin and its …

Central nervous system regulation of food intake and energy expenditure: role of galanin-mediated feeding behavior

PH Fang, M Yu, YP Ma, J Li, YM Sui… - Neuroscience bulletin, 2011 - ncbi.nlm.nih.gov
Galanin is a neuropeptide widely expressed in the brain. It is implicated in energy
expenditure, feeding, and the regulation of body weight. Numerous studies have revealed …

Relationship between clinical characteristics of narcolepsy and CSF orexin‐A levels

M Nakamura, T Kanbayashi, T Sugiura… - Journal of sleep …, 2011 - Wiley Online Library
Although an abnormally low cerebrospinal fluid (CSF)‐orexin level is well known to be a
specific finding in narcoleptic patients, the relationships between the severity of the core …

Central Nervous System Lipocalin‐Type Prostaglandin D2‐Synthase is Correlated with Orexigenic Neuropeptides, Visceral Adiposity and Markers of the …

E Elias, A Benrick, CJ Behre, R Ekman… - Journal of …, 2011 - Wiley Online Library
Lipocalin‐type prostaglandin D2‐synthase (L‐PGDS) is the main producer of prostaglandin
D2 (PGD2) in the central nervous system (CNS). Animal data suggest effects of central …

甘丙肽与非酒精性脂肪性肝病重要危险因素及病理生理机制关系研究进展

李郑红, 陈源文, 徐雷鸣 - 胃肠病学和肝病学杂志, 2011 - cqvip.com
胰岛素抵抗和炎症反应是非酒精性脂肪性肝病(NAFLD) 主要发病机制, 以肥胖, Ⅱ
型糖尿病和高脂血症为代表的代谢综合征是其主要危险因素. 甘丙肽作为神经肽和脂肪因子 …