Mitochondrial dysfunction in Parkinson′ s disease
Parkinson′ s disease (PD) is a progressive, neurodegenerative condition that has
increasingly been linked with mitochondrial dysfunction and inhibition of the electron …
increasingly been linked with mitochondrial dysfunction and inhibition of the electron …
Chronic deprivation of TrkB signaling leads to selective late-onset nigrostriatal dopaminergic degeneration
M Baydyuk, MT Nguyen, B Xu - Experimental neurology, 2011 - Elsevier
The pathological hallmark of Parkinson's disease (PD) is a selective and progressive loss of
dopaminergic (DA) neurons in the substantia nigra pars compacta (SNc). In the vast majority …
dopaminergic (DA) neurons in the substantia nigra pars compacta (SNc). In the vast majority …
Dopaminergic and behavioral correlates of progressive lesioning of the nigrostriatal pathway with 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine
NRS Goldberg, AK Haack, NS Lim, OK Janson… - Neuroscience, 2011 - Elsevier
A number of neurotoxin-and gene-based rodent models of acute neurodegeneration of
nigrostriatal dopamine (DA) neurons are used to study Parkinson's disease (PD). The rapid …
nigrostriatal dopamine (DA) neurons are used to study Parkinson's disease (PD). The rapid …
[图书][B] Chronic Antidepressant Treatment in the Nigrostriatal System: the Impact of Antidepressant-Mediated Neuroplasticity
KL Paumier - 2011 - search.proquest.com
The studies in this dissertation are designed to address whether antidepressant-mediated
neuroplasticity can benefit Parkinson's disease (PD). The first aim investigates whether …
neuroplasticity can benefit Parkinson's disease (PD). The first aim investigates whether …
Neuroprotection in Parkinson's Disease
A Pascual, J Villadiego, M Hidalgo-Figueroa… - 2011 - books.rsc.org
Neurotrophic factors (NTFs) are small natural proteins necessary for the development and
survival of nerve cells as well as for the maintenance of their morphological and functional …
survival of nerve cells as well as for the maintenance of their morphological and functional …
Animal Models of Parkinson's
HJ Rideout, L Stefanis - Animal Models for Neurodegenerative …, 2011 - books.google.com
Parkinson's disease (PD) is a common progressive, neurodegenerative disorder,
characterized predominantly by motor symptoms such as tremor, rigidity and bradykinesia …
characterized predominantly by motor symptoms such as tremor, rigidity and bradykinesia …
[图书][B] Exendin-4 promotes recovery of both behavioural and neurochemical deficits in a" pre-motor" rodent model of Parkinson's disease
N Rampersaud - 2011 - search.proquest.com
Research on Parkinson's disease (PD) has mainly focused on the degeneration of the
dopaminergic neurons of nigro-striatal (NS) pathway; however, post-mortem studies have …
dopaminergic neurons of nigro-striatal (NS) pathway; however, post-mortem studies have …
THE MPTP MOUSE MODEL OF PARKINSON'S DISEASE: THE TRUE, THE FALSE, AND THE UNKNOWN
VJLS PRZEDBORSKI - Parkinson's Disease: Molecular and …, 2011 - books.google.com
Parkinson's disease (PD) appears to be the second most frequent degenerative disorder of
the nervous system in elderly next to the dementia of Alzheimer's. In part, because a of …
the nervous system in elderly next to the dementia of Alzheimer's. In part, because a of …
[引用][C] Chronic exposure to manganese interacts with striatal dopamine turnover in human alpha-synuclein transgenic mice
T Peneder - 2011 - na