PET–CT for radiotherapy treatment planning and response monitoring in solid tumors

J Bussink, JHAM Kaanders… - Nature Reviews …, 2011 - nature.com
PET imaging has evolved as an indispensible tool for staging in oncology. Multiple
quantitative measurements can be performed, enabling the effects of treatment to be …

The promise and pitfalls of positron emission tomography and single-photon emission computed tomography molecular imaging–guided radiation therapy

RL Wahl, JM Herman, E Ford - Seminars in radiation oncology, 2011 - Elsevier
External beam radiation therapy procedures have, until recently, been planned almost
exclusively using anatomic imaging methods. Molecular imaging using hybrid positron …

Gradient-based delineation of the primary GTV on FDG-PET in non-small cell lung cancer: a comparison with threshold-based approaches, CT and surgical …

M Wanet, JA Lee, B Weynand, M De Bast… - Radiotherapy and …, 2011 - Elsevier
PURPOSE: The aim of this study was to validate a gradient-based segmentation method for
GTV delineation on FDG-PET in NSCLC through surgical specimen, in comparison with …

Final results of the randomized phase III CHARTWEL-trial (ARO 97-1) comparing hyperfractionated-accelerated versus conventionally fractionated radiotherapy in non …

M Baumann, T Herrmann, R Koch… - Radiotherapy and …, 2011 - Elsevier
BACKGROUND: Continuous hyperfractionated accelerated radiotherapy (CHART)
counteracts repopulation and may significantly improve outcome of patients with non-small …

[HTML][HTML] Optimal gating compared to 3D and 4D PET reconstruction for characterization of lung tumours

W Van Elmpt, J Hamill, J Jones… - European journal of …, 2011 - Springer
Purpose We investigated the added value of a new respiratory amplitude-based PET
reconstruction method called optimal gating (OG) with the aim of providing accurate image …

The maximum standardized uptake value (SUVmax) on FDG-PET is a strong predictor of local recurrence for localized non-small-cell lung cancer after stereotactic …

A Takeda, N Yokosuka, T Ohashi, E Kunieda… - Radiotherapy and …, 2011 - Elsevier
BACKGROUND: The maximum standardized uptake value (SUVmax) of FDG-PET may
predict local recurrence for localized non-small-cell lung cancer (NSCLC) after stereotactic …

Dose painting by contours versus dose painting by numbers for stage II/III lung cancer: practical implications of using a broad or sharp brush

G Meijer, J Steenhuijsen, M Bal, K De Jaeger… - Radiotherapy and …, 2011 - Elsevier
PURPOSE: Local recurrence rates are high in patients with locally advanced NSCLC treated
with 60 to 66Gy in 2Gy fractions. It is hypothesised that boosting volumes with high SUV on …

Therapeutic implications of molecular imaging with PET in the combined modality treatment of lung cancer

J van Loon, A van Baardwijk, L Boersma, M Öllers… - Cancer treatment …, 2011 - Elsevier
Molecular imaging with PET, and certainly integrated PET-CT, combining functional and
anatomical imaging, has many potential advantages over anatomical imaging alone in the …

Dealing with geometric uncertainties in dose painting by numbers: introducing the ΔVH

M Witte, G Shakirin, A Houweling, H Peulen… - Radiotherapy and …, 2011 - Elsevier
PURPOSE: Dose painting by numbers lacks the conventional margin approach for
geometric uncertainties. Moreover, the DVH is unable to assess the geometric accuracy of a …

Generating lung tumor internal target volumes from 4D‐PET maximum intensity projections

JM Lamb, C Robinson, J Bradley, R Laforest… - Medical …, 2011 - Wiley Online Library
Purpose: Positron emission tomography (PET) of lung tumors suffers from breathing‐motion
induced blurring. Respiratory‐correlated PET ameliorates motion blurring and enables …