Spinal cord injuries (SCI) can result in devastating paralysis, for which there is currently no
robustly efficacious neuroprotective/neuroregenerative treatment. When the spinal cord is …

Spinal cord injury (SCI) is a traumatic disorder resulting in a functional deficit that usually
leads to severe and permanent paralysis. After the initial insult to the spinal cord, additional …

Rothman-Simeone The Spine helps you achieve optimal outcomes in the clinical practice of
spine surgery in adults and children. Drs. Harry N. Herkowitz, Steven R. Garfin, Frank J …

BACKGROUND: Traumatic spinal cord injury (SCI) is a major cause of long-term disability.
However, therapeutic agents targeting SCI are sorely lacking. The aim of this study was to …

Spinal cord injury (SCI) triggers inflammatory responses that involve neutrophils,
macrophages/microglia and astrocytes and molecules that potentially cause secondary …

As one of trials on neuroprotection after spinal cord injury, we used pregabalin. After spinal
cord injury (SCI) in rats using contusion model, we observed the effect of pregabalin …

Spinal cord injuries in mammals, including humans, have devastating long-term
consequences. Despite substantial research, therapeutic approaches developed in …

Objective: To determine the cellular and molecular mechanisms by which acid-sensing ion
channel 1a (ASIC1a) plays its role in the secondary injury after traumatic spinal cord injury …

BACKGROUND: Inflammation plays an important role in the pathogenesis of secondary
damage after spinal cord injury (SCI). Previous studies have suggested that nuclear factor …

Objective Minocycline, a second-generation tetracycline-class antibiotic, has been well
established to exert a neuroprotective effect in animal models and neurodegenerative …