Stimulating natural killer cells to protect against cancer: recent developments
A Gillgrass, A Ashkar - Expert review of clinical immunology, 2011 - Taylor & Francis
Current cancer immunotherapies have begun to target cell types involved in innate
immunity, such as natural killer (NK) cells that recognize and kill tumor cells. Recent …
immunity, such as natural killer (NK) cells that recognize and kill tumor cells. Recent …
[HTML][HTML] Uropathogenic E. coli infection provokes epigenetic downregulation of CDKN2A (p16INK4A) in uroepithelial cells
C Tolg, N Sabha, R Cortese, T Panchal, A Ahsan… - Laboratory …, 2011 - Elsevier
Host cell and bacterial factors determine severity and duration of infections. To allow for
bacteria pathogenicity and persistence, bacteria have developed mechanisms that modify …
bacteria pathogenicity and persistence, bacteria have developed mechanisms that modify …
Intramacrophage survival of uropathogenic Escherichia coli: differences between diverse clinical isolates and between mouse and human macrophages
Uropathogenic E. coli (UPEC) are the primary cause of urinary tract infections. Recent
studies have demonstrated that UPEC can invade and replicate within epithelial cells …
studies have demonstrated that UPEC can invade and replicate within epithelial cells …
[HTML][HTML] A novel adjuvant Ling Zhi-8 enhances the efficacy of DNA cancer vaccine by activating dendritic cells
CC Lin, YL Yu, CC Shih, KJ Liu, KL Ou… - Cancer Immunology …, 2011 - Springer
DNA vaccine has been suggested to use in cancer therapy, but the efficacy remains to be
improved. The immunostimulatory effect of a fungal immunomodulatory protein Ling Zhi-8 …
improved. The immunostimulatory effect of a fungal immunomodulatory protein Ling Zhi-8 …
FimH, a TLR4 ligand, induces innate antiviral responses in the lung leading to protection against lethal influenza infection in mice
MF Abdul-Careem, MF Mian, AE Gillgrass… - Antiviral research, 2011 - Elsevier
Fimbriae H protein (FimH) is a novel TLR4 ligand that has been shown to stimulate the
innate immune system and elicits protective responses against bacterial and viral infections …
innate immune system and elicits protective responses against bacterial and viral infections …
[HTML][HTML] Bacterial-Epithelial Contact Is a Key Determinant of Host Innate Immune Responses to Enteropathogenic and Enteroaggregative Escherichia coli
LA Edwards, M Bajaj-Elliott, NJ Klein, SH Murch… - PLoS …, 2011 - journals.plos.org
Background Enteropathogenic (EPEC) and Enteroaggregative (EAEC) E. coli have similar,
but distinct clinical symptoms and modes of pathogenesis. Nevertheless when they infect the …
but distinct clinical symptoms and modes of pathogenesis. Nevertheless when they infect the …
[HTML][HTML] The ectodomain of the Toll-like receptor 4 prevents constitutive receptor activation
G Panter, R Jerala - Journal of Biological Chemistry, 2011 - ASBMB
Toll-like receptor 4 (TLR4) is involved in activation of the innate immune response in a large
number of different diseases. Despite numerous studies, the role of separate domains of …
number of different diseases. Despite numerous studies, the role of separate domains of …
Endometrial Epithelial Cell Responses to Coinfecting Viral and Bacterial Pathogens in the Genital Tract Can Activate the HIV-1 LTR in an NFκB-and AP-1–Dependent …
Abstract Background. Sexually transmitted infections (STIs) are associated with increased
human immunodeficiency virus type 1 (HIV-1) susceptibility and viral shedding in the genital …
human immunodeficiency virus type 1 (HIV-1) susceptibility and viral shedding in the genital …
[HTML][HTML] SlyA protein activates fimB gene expression and type 1 fimbriation in Escherichia coli K-12
G McVicker, L Sun, BK Sohanpal, K Gashi… - Journal of Biological …, 2011 - ASBMB
We have demonstrated that SlyA activates fimB expression and hence type 1 fimbriation, a
virulence factor in Escherichia coli. SlyA is shown to bind to two operator sites (O SA1 and O …
virulence factor in Escherichia coli. SlyA is shown to bind to two operator sites (O SA1 and O …
Regulation of cyclooxygenase‐2 expression in human bladder epithelial cells infected with type I fimbriated uropathogenic E. coli
TC Chen, JP Tsai, HJ Huang, CC Teng… - Cellular …, 2011 - Wiley Online Library
The type 1 fimbriae of uropathogenic Escherichia coli (UPEC) have been described as
important for the establishment of bladder infections and urinary tract infections (UTI) …
important for the establishment of bladder infections and urinary tract infections (UTI) …