Vaccines represent one of the greatest triumphs of modern medicine. Despite the common
origins of vaccinology and immunology more than 200 years ago, the two disciplines have …

Dendritic cells (DCs) and natural killer (NK) cells have central roles in antiviral immunity by
shaping the quality of the adaptive immune response to viruses and by mediating direct …

Background The genetic analysis of human primary immunodeficiencies has defined the
contribution of specific cell populations and molecular pathways in the host defense against …

Macrophage and dendritic cell (DC) are hematopoietic cells found in all tissues in the steady
state that share the ability to sample the environment but have distinct function in tissue …

Human hematolymphoid mice have become valuable tools for the study of human
hematopoiesis and uniquely human pathogens in vivo. Recent improvements in …

Mouse dendritic cells (DC) have been extensively studied in various tissues, especially
spleen, and they comprise subsets with distinct developmental origins, surface phenotypes …

Subsets of dendritic cells (DCs) have been described according to their functions and
anatomical locations. Conventional DC subsets are defined by reciprocal expression of …

Three surface molecules of mouse CD8+ dendritic cells (DCs), also found on the equivalent
human DC subpopulation, were compared as targets for Ab-mediated delivery of Ags, a …

In Sjögren's syndrome, like in most other autoimmune diseases, the enigma leading to a
pathogenic attack against self has not yet been solved. By definition, the disease must be …

Maturation of dendritic cells (DC) to competent APC is essential for the generation of
acquired immunity and is a major function of adjuvants. dsRNA, a molecular signature of …