Epigenetics and colorectal cancer
VV Lao, WM Grady - Nature reviews Gastroenterology & hepatology, 2011 - nature.com
Colorectal cancer (CRC) is a leading cause of cancer deaths worldwide. It results from an
accumulation of genetic and epigenetic changes in colon epithelial cells, which transforms …
accumulation of genetic and epigenetic changes in colon epithelial cells, which transforms …
TGFBR2 and BAX Mononucleotide Tract Mutations, Microsatellite Instability, and Prognosis in 1072 Colorectal Cancers
K Shima, T Morikawa, M Yamauchi, A Kuchiba… - PLoS …, 2011 - journals.plos.org
Background Mononucleotide tracts in the coding regions of the TGFBR2 and BAX genes are
commonly mutated in microsatellite instability-high (MSI-high) colon cancers. The receptor …
commonly mutated in microsatellite instability-high (MSI-high) colon cancers. The receptor …
Body size and colorectal cancer risk after 16.3 years of follow-up: an analysis from the Netherlands Cohort Study
LAE Hughes, CCJM Simons… - American journal of …, 2011 - academic.oup.com
A large body size may differentially influence risk of colorectal cancer (CRC) by anatomic
location. The Netherlands Cohort Study includes 120,852 men and women aged 55–69 …
location. The Netherlands Cohort Study includes 120,852 men and women aged 55–69 …