Expanding fungal pathogenesis: Cryptococcus breaks out of the opportunistic box
JW Kronstad, R Attarian, B Cadieux, J Choi… - Nature reviews …, 2011 - nature.com
Cryptococcus neoformans is generally considered to be an opportunistic fungal pathogen
because of its tendency to infect immunocompromised individuals, particularly those …
because of its tendency to infect immunocompromised individuals, particularly those …
The TB Structural Genomics Consortium: a decade of progress
The TB Structural Genomics Consortium is a worldwide organization of collaborators whose
mission is the comprehensive structural determination and analyses of Mycobacterium …
mission is the comprehensive structural determination and analyses of Mycobacterium …
Cell wall chitosan is necessary for virulence in the opportunistic pathogen Cryptococcus neoformans
LG Baker, CA Specht, JK Lodge - Eukaryotic cell, 2011 - Am Soc Microbiol
Cryptococcus neoformans is an opportunistic fungal pathogen that causes
meningoencephalitis. Its cell wall is composed of glucans, proteins, chitin, and chitosan …
meningoencephalitis. Its cell wall is composed of glucans, proteins, chitin, and chitosan …
Dynamics of Cryptococcus neoformans-macrophage interactions reveal that fungal background influences outcome during cryptococcal meningoencephalitis in …
A Alanio, M Desnos-Ollivier, F Dromer - MBio, 2011 - Am Soc Microbiol
Cryptococcosis is a multifaceted fungal infection with variable clinical presentation and
outcome. As in many infectious diseases, this variability is commonly assigned to host …
outcome. As in many infectious diseases, this variability is commonly assigned to host …
Toward an Integrated Model of Capsule Regulation in Cryptococcus neoformans
BC Haynes, ML Skowyra, SJ Spencer, SR Gish… - PLoS …, 2011 - journals.plos.org
Cryptococcus neoformans is an opportunistic fungal pathogen that causes serious human
disease in immunocompromised populations. Its polysaccharide capsule is a key virulence …
disease in immunocompromised populations. Its polysaccharide capsule is a key virulence …
Role of IL-17A on Resolution of Pulmonary C. neoformans Infection
The current studies evaluated the role of interleukin (IL)-17A in the induction of protective
immunity against pulmonary cryptococcosis in mice. Protection against pulmonary infection …
immunity against pulmonary cryptococcosis in mice. Protection against pulmonary infection …
Cryptococcus neoformans requires a functional glycolytic pathway for disease but not persistence in the host
MS Price, M Betancourt-Quiroz, JL Price, DL Toffaletti… - MBio, 2011 - Am Soc Microbiol
Cryptococcus neoformans is an important fungal pathogen of immunocompromised
individuals, with a close relative, Cryptococcus gattii, emerging as a serious threat for the …
individuals, with a close relative, Cryptococcus gattii, emerging as a serious threat for the …
Role for Golgi reassembly and stacking protein (GRASP) in polysaccharide secretion and fungal virulence
L Kmetzsch, LS Joffe, CC Staats… - Molecular …, 2011 - Wiley Online Library
Secretion of virulence factors is a critical mechanism for the establishment of cryptococcosis,
a disease caused by the yeast pathogen Cryptococcus neoformans. One key virulence …
a disease caused by the yeast pathogen Cryptococcus neoformans. One key virulence …
Nitrogen Metabolite Repression of Metabolism and Virulence in the Human Fungal Pathogen Cryptococcus neoformans
IR Lee, EWL Chow, CA Morrow, JT Djordjevic… - Genetics, 2011 - academic.oup.com
Proper regulation of metabolism is essential to maximizing fitness of organisms in their
chosen environmental niche. Nitrogen metabolite repression is an example of a regulatory …
chosen environmental niche. Nitrogen metabolite repression is an example of a regulatory …
Cryptococcus gattii Virulence Composite: Candidate Genes Revealed by Microarray Analysis of High and Less Virulent Vancouver Island Outbreak Strains
P Ngamskulrungroj, J Price, T Sorrell, JR Perfect… - PLoS …, 2011 - journals.plos.org
Human and animal cryptococcosis due to an unusual molecular type of Cryptococcus gattii
(VGII) emerged recently on Vancouver Island, Canada. Unlike C. neoformans, C. gattii …
(VGII) emerged recently on Vancouver Island, Canada. Unlike C. neoformans, C. gattii …