RAS oncogenes: weaving a tumorigenic web

Y Pylayeva-Gupta, E Grabocka, D Bar-Sagi - Nature Reviews Cancer, 2011 - nature.com
RAS proteins are essential components of signalling pathways that emanate from cell
surface receptors. Oncogenic activation of these proteins owing to missense mutations is …

Microparticles in angiogenesis: therapeutic potential

MC Martinez, R Andriantsitohaina - Circulation research, 2011 - Am Heart Assoc
Considered during the past decades as cell dust, microparticles are now deemed true
biomarkers and vectors of biological information between cells. Depending on their origin …

Mathematical modeling of cancer cell invasion of tissue: biological insight from mathematical analysis and computational simulation

V Andasari, A Gerisch, G Lolas, AP South… - Journal of mathematical …, 2011 - Springer
The ability of cancer cells to break out of tissue compartments and invade locally gives solid
tumours a defining deadly characteristic. One of the first steps of invasion is the remodelling …

Decidualisation and angiogenesis

M Plaisier - Best practice & research Clinical obstetrics & …, 2011 - Elsevier
The timing of decidualisation and vascular processes during the implantation period is of
paramount importance for the development of a receptive endometrium suitable for …

Annexin A2 promotes glioma cell invasion and tumor progression

H Zhai, S Acharya, I Gravanis, S Mehmood… - Journal of …, 2011 - Soc Neuroscience
Gliomas are highly invasive, lethal brain tumors. Tumor-associated proteases play an
important role in glioma progression. Annexin A2 is overexpressed in many cancers and …

[HTML][HTML] Controlled protein delivery based on enzyme-responsive nanocapsules

J Wen, SM Anderson, J Du, M Yan, J Wang… - … (Deerfield Beach, Fla …, 2011 - ncbi.nlm.nih.gov
Enzyme-responsive protein nanocapsules are synthesized to release their protein cargoes
in response to specific enzymes secreted in certain cellular events not only with specificity …

Regulation of fibrinolysis by S100A10 in vivo

AP Surette, PA Madureira, KD Phipps… - Blood, The Journal …, 2011 - ashpublications.org
Endothelial cells form the inner lining of vascular networks and maintain blood fluidity by
inhibiting blood coagulation and promoting blood clot dissolution (fibrinolysis). Plasmin, the …

Notch modulates VEGF action in endothelial cells by inducing Matrix Metalloprotease activity

Y Funahashi, CJ Shawber, A Sharma, E Kanamaru… - Vascular cell, 2011 - Springer
Abstract Background In the vasculature, Notch signaling functions as a downstream effecter
of Vascular Endothelial Growth Factor (VEGF) signaling. VEGF regulates sprouting …

Molecular imaging in cancer treatment

MH Michalski, X Chen - European journal of nuclear medicine and …, 2011 - Springer
The success of cancer therapy can be difficult to predict, as its efficacy is often predicated
upon characteristics of the cancer, treatment, and individual that are not fully understood or …

The role of vascular actors in two dimensional dialogue of human bone marrow stromal cell and endothelial cell for inducing self-assembled network

H Li, R Daculsi, M Grellier, R Bareille, C Bourget… - PloS one, 2011 - journals.plos.org
Angiogenesis is very important for vascularized tissue engineering. In this study, we found
that a two-dimensional co-culture of human bone marrow stromal cell (HBMSC) and human …