Analytical aspects of microRNA in diagnostics: a review

M de Planell-Saguer, MC Rodicio - Analytica chimica acta, 2011 - Elsevier
MicroRNAs (miRNA) are short (∼ 22 nucleotides) non-coding RNA molecules that regulate
gene expression at the post-transcriptional level. Their expression is specific to cells and …

MicroRNA signatures: clinical biomarkers for the diagnosis and treatment of breast cancer

CA Andorfer, BM Necela, EA Thompson… - Trends in molecular …, 2011 - cell.com
Recognition that breast cancer is a heterogeneous disease in which each patient's tumor
has specific characteristics has led to a search for biomarkers and combinations of markers …

Investigation of miR-21, miR-141, and miR-221 in blood circulation of patients with prostate cancer

F Yaman Agaoglu, M Kovancilar, Y Dizdar… - Tumor Biology, 2011 - Springer
In addition to their potential as tissue-based markers for cancer classification and
prognostication, the study of microRNAs (miRNAs) in blood circulation is also of interest. In …

MicroRNAs are associated with human embryo implantation defects

A Revel, H Achache, J Stevens, Y Smith… - Human …, 2011 - academic.oup.com
BACKGROUND Repeated implantation failure (RIF) is a major problem encountered in IVF.
We have previously reported that RIF-IVF patients have a different endometrial gene …

[HTML][HTML] Non-coding RNAs in cancer initiation and progression and as novel biomarkers

SP Nana-Sinkam, CM Croce - Molecular oncology, 2011 - Elsevier
Cancer represents a complex group of heterogeneous diseases. While many cancers share
fundamental biological processes (hallmarks of cancer) necessary for their development …

MicroRNAs as biomarkers of disease onset

M Ciesla, K Skrzypek, M Kozakowska… - Analytical and …, 2011 - Springer
MicroRNAs (miRNAs) are small, noncoding RNA molecules with the ability to
posttranscriptionally regulate gene expression via targeting the 3′ untranslated region of …

[HTML][HTML] Persistent upregulation of U6: SNORD44 small RNA ratio in the serum of breast cancer patients

HN Appaiah, CP Goswami, LA Mina, S Badve… - Breast Cancer …, 2011 - Springer
Introduction Serum microRNAs have the potential to be valuable biomarkers of cancer. This
investigation addresses two issues that impact their utility: a) appropriate normalization …

[HTML][HTML] Micro-RNAs as diagnostic or prognostic markers in human epithelial malignancies

A Hui, C How, E Ito, FF Liu - BMC cancer, 2011 - Springer
Micro-RNAs (miRs) are important regulators of mRNA and protein expression; the ability of
miR expression profilings to distinguish different cancer types and classify their sub-types …

[HTML][HTML] Circulating microRNAs as minimally invasive biomarkers for cancer theragnosis and prognosis

WCS Cho - Frontiers in genetics, 2011 - frontiersin.org
Novel cancer biomarker discovery is urgently needed for cancer theragnosis and prognosis,
and among the many possible types of samples, blood is regarded to be ideal for this …

Tissular and soluble miRNAs for diagnostic and therapy improvement in digestive tract cancers

R Albulescu, M Neagu, L Albulescu… - Expert review of …, 2011 - Taylor & Francis
Digestive cancers (eg, gastric, colorectal, pancreatic or hepatocarcinoma) are among the
most frequently reported cancers in the world, and are characterized by invasivity, metastatic …