A genome-wide association study confirms APOE as the major gene influencing survival in long-lived individuals
A Nebel, R Kleindorp, A Caliebe, M Nothnagel… - Mechanisms of ageing …, 2011 - Elsevier
We conducted a case–control genome-wide association study (GWAS) of human longevity,
comparing 664,472 autosomal SNPs in 763 long-lived individuals (LLI; mean age: 99.7 …
comparing 664,472 autosomal SNPs in 763 long-lived individuals (LLI; mean age: 99.7 …
[HTML][HTML] A genome-wide association study of aging
Human longevity and healthy aging show moderate heritability (20%–50%). We conducted
a meta-analysis of genome-wide association studies from 9 studies from the Cohorts for …
a meta-analysis of genome-wide association studies from 9 studies from the Cohorts for …
Genetic Variation in the CYP2C Monooxygenase Enzyme Subfamily Shows No Association With Longevity in a German Population
F Flachsbart, M Ufer, R Kleindorp… - … Series A: Biomedical …, 2011 - academic.oup.com
Cytochrome P450 enzymes, especially the CYP2C subfamily, are involved in the generation
of reactive oxygen species and are regarded as susceptibility factors for age-related …
of reactive oxygen species and are regarded as susceptibility factors for age-related …
[PDF][PDF] Selection for longevity in a polygamous society in rural Africa
D van Bodegom, L May, H Meij… - … survival in a …, 2011 - scholarlypublications …
Human longevity was long thought to be non-adaptive, resulting from better environmental
conditions. Later, a selective advantage of grandmothers has been suggested. Recently, it …
conditions. Later, a selective advantage of grandmothers has been suggested. Recently, it …
Determinants of Healthy Ageing
S Walter - pure.eur.nl
HEALTHY AGEING Page 1 DETERMINANTS OF HEALTHY AGEING StudieS of diSability and
Survival among the elderly D E T E R M IN A N T S O F H E A L T H Y A G E IN G S t u d ie S o f …
Survival among the elderly D E T E R M IN A N T S O F H E A L T H Y A G E IN G S t u d ie S o f …