Post‐translational modifications of histones elicit structural and functional changes within
chromatin that regulate various epigenetic processes. Epigenetic mechanisms rely on …

B-cell non-Hodgkin's lymphoma comprises biologically and clinically distinct diseases the
pathogenesis of which is associated with genetic lesions affecting oncogenes and tumour …

Relapsed acute lymphoblastic leukaemia (ALL) is a leading cause of death due to disease
in young people, but the biological determinants of treatment failure remain poorly …

Protein acetylation has emerged as a major mechanism in regulating cellular metabolism.
Whereas most glycolytic steps are reversible, the reaction catalyzed by pyruvate kinase is …

Transcriptional co-activator p300, which contains an intrinsic histone acetyltransferase
activity, is required for an array of important cellular processes. Tight control of p300 function …

The co-translational modification of N-terminal acetylation is ubiquitous among eukaryotes
and has been reported to have a wide range of biological effects. The human N-terminal …

Abstract Characterization of the molecular function of complex phenols naturally present in
extra virgin olive oil (EVOO) against the HER2-gene amplified JIMT-1 cell line, a unique …

After entry into the target cell and reverse transcription, HIV-1 genes are integrated into the
host genome. It is now well established that the viral promoter activity is directly governed by …

Pax5/B cell lineage specific activator protein (BSAP) is a B lineage-specific regulator that
controls the B lineage-specific gene expression program and immunoglobulin gene VH to …

Bisubstrate‐type compound Lys‐CoA has been shown to inhibit the p300 histone acetyl
transferase activity efficiently and may constitute a lead compound for a novel class of …