Diagnostic potential of saliva: current state and future applications

T Pfaffe, J Cooper-White, P Beyerlein… - Clinical …, 2011 - academic.oup.com
BACKGROUND Over the past 10 years, the use of saliva as a diagnostic fluid has gained
attention and has become a translational research success story. Some of the current …

Saliva as a diagnostic fluid

D Malamud - Dental Clinics, 2011 - dental.theclinics.com
Saliva is a clinically informative, biologic fluid (biofluid) that is useful for novel approaches to
prognosis, laboratory or clinical diagnosis, and monitoring and management of patients with …

Saliva: diagnostics and therapeutic perspectives

N Spielmann, DT Wong - Oral diseases, 2011 - Wiley Online Library
Oral Diseases (2011) 17, 345–354 For the past two decades, salivary diagnostic
approaches have been developed to monitor oral diseases such as periodontal diseases …

Defining salivary biomarkers using mass spectrometry-based proteomics: a systematic review

SK Al-Tarawneh, MB Border, CF Dibble… - Omics: a journal of …, 2011 - liebertpub.com
Recent advancements in mass spectrometric proteomics provide a promising result in
utilizing saliva to explore biomarkers for diagnostic purposes. However, the issues of …

Oral squamous cell carcinoma detection by salivary biomarkers in a Serbian population

O Brinkmann, DA Kastratovic, MV Dimitrijevic… - Oral oncology, 2011 - Elsevier
Early detection of oral squamous cell cancer (OSCC) is the key to improve the low 5-year
survival rate. Using proteomic and genomic technologies we have previously discovered …

Recovering circulating extracellular or cell-free RNA from bodily fluids

G Tzimagiorgis, EZ Michailidou, A Kritis… - Cancer …, 2011 - Elsevier
The presence of extracellular circulating or cell-free RNA in biological fluids is becoming a
promising diagnostic tool for non invasive and cost effective cancer detection. Extracellular …

Proteomic analysis of saliva: a unique tool to distinguish primary Sjögren's syndrome from secondary Sjögren's syndrome and other sicca syndromes

C Baldini, L Giusti, F Ciregia, Y Da Valle… - Arthritis research & …, 2011 - Springer
Introduction A growing interest has arisen in salivary proteomics as a tool for the
identification of biomarkers for primary Sjögren's syndrome (pSS). Nonetheless, only a …

Saliva: A diagnostic biomarker of periodontal diseases

PB Patil, BR Patil - Journal of Indian Society of Periodontology, 2011 - journals.lww.com
Early detection of disease plays a crucial role in successful therapy. Early diagnosis and
management reduces the severity and possible complications of the disease process. To …

Identification of autoantibody biomarkers for primary Sjögren's syndrome using protein microarrays

S Hu, A Vissink, M Arellano, C Roozendaal… - …, 2011 - Wiley Online Library
Sjögren's syndrome (SS) is a chronic, progressive autoimmune disease primarily affecting
women. Diagnosis of SS requires an invasive salivary gland tissue biopsy and a long delay …

Activation of the interferon pathway in peripheral blood of patients with Sjögren's syndrome

O Kimoto, J Sawada, K Shimoyama, D Suzuki… - The Journal of …, 2011 - jrheum.org
Objective. DNA microarray analysis and quantitative real-time polymerase chain reaction
(PCR) were performed to identify key target genes in peripheral blood from patients with …