From 3D cell culture to organs-on-chips
3D cell-culture models have recently garnered great attention because they often promote
levels of cell differentiation and tissue organization not possible in conventional 2D culture …
levels of cell differentiation and tissue organization not possible in conventional 2D culture …
Hyaluronic acid hydrogels for biomedical applications
JA Burdick, GD Prestwich - Advanced materials, 2011 - Wiley Online Library
Hyaluronic acid (HA), an immunoneutral polysaccharide that is ubiquitous in the human
body, is crucial for many cellular and tissue functions and has been in clinical use for over …
body, is crucial for many cellular and tissue functions and has been in clinical use for over …
[PDF][PDF] Omnidirectional printing of 3D microvascular networks
W Wu, A DeConinck, JA Lewis - Advanced materials, 2011 - lewisgroup.seas.harvard.edu
Nature is replete with examples of microvascular systems that enable efficient fluid flow and
distribution for autonomic healing, cooling, and energy harvesting. Emulating these systems …
distribution for autonomic healing, cooling, and energy harvesting. Emulating these systems …
Microfluidic devices for bioapplications
Harnessing the ability to precisely and reproducibly actuate fluids and manipulate
bioparticles such as DNA, cells, and molecules at the microscale, microfluidics is a powerful …
bioparticles such as DNA, cells, and molecules at the microscale, microfluidics is a powerful …
Controlling the porosity of fibrous scaffolds by modulating the fiber diameter and packing density
Porosity has been shown to be a key determinant of the success of tissue engineered
scaffolds. A high degree of porosity and an appropriate pore size are necessary to provide …
scaffolds. A high degree of porosity and an appropriate pore size are necessary to provide …
Synthesis and characterization of tunable poly (ethylene glycol): gelatin methacrylate composite hydrogels
Poly (ethylene glycol)(PEG) hydrogels are popular for cell culture and tissue-engineering
applications because they are nontoxic and exhibit favorable hydration and nutrient …
applications because they are nontoxic and exhibit favorable hydration and nutrient …
Simultaneous regeneration of articular cartilage and subchondral bone in vivo using MSCs induced by a spatially controlled gene delivery system in bilayered …
J Chen, H Chen, P Li, H Diao, S Zhu, L Dong, R Wang… - Biomaterials, 2011 - Elsevier
Engineering complex tissues is important but difficult to achieve in tissue regeneration.
Osteochondral tissue engineering for the repair of osteochondral defect, involving …
Osteochondral tissue engineering for the repair of osteochondral defect, involving …
Functional tooth regeneration using a bioengineered tooth unit as a mature organ replacement regenerative therapy
M Oshima, M Mizuno, A Imamura, M Ogawa… - PloS one, 2011 - journals.plos.org
Donor organ transplantation is currently an essential therapeutic approach to the
replacement of a dysfunctional organ as a result of disease, injury or aging in vivo. Recent …
replacement of a dysfunctional organ as a result of disease, injury or aging in vivo. Recent …
Vascular tissue engineering: towards the next generation vascular grafts
The application of tissue engineering technology to cardiovascular surgery holds great
promise for improving outcomes in patients with cardiovascular diseases. Currently used …
promise for improving outcomes in patients with cardiovascular diseases. Currently used …
Three-dimensional biomaterials for the study of human pluripotent stem cells
TP Kraehenbuehl, R Langer, LS Ferreira - Nature methods, 2011 - nature.com
The self-renewal and differentiation of human pluripotent stem cells (hPSCs) have typically
been studied in flat, two-dimensional (2D) environments. In this Perspective, we argue that …
been studied in flat, two-dimensional (2D) environments. In this Perspective, we argue that …