Molecular pathways in colorectal cancer

S Al‐Sohaily, A Biankin, R Leong… - Journal of …, 2012 - Wiley Online Library
Colorectal cancer (CRC) is the second most common newly diagnosed cancer and accounts
for the second highest number of cancer related deaths in Australia, the third worldwide and …

Implication of microsatellite instability in human gastric cancers

U Shokal, PC Sharma - Indian Journal of Medical Research, 2012 - journals.lww.com
Microsatellite instability, one of the phenomena implicated in gastric cancer, is mainly
associated with the expansion or contraction of microsatellite sequences due to replication …

[HTML][HTML] Evaluation of magnifying colonoscopy in the diagnosis of serrated polyps

S Ishigooka, M Nomoto, N Obinata, Y Oishi… - World journal of …, 2012 - ncbi.nlm.nih.gov
AIM: To elucidate the colonoscopic features of serrated lesions of the colorectum using
magnifying colonoscopy. METHODS: Broad division of serrated lesions of the colorectum …

Outcomes of a 5-year follow-up of patients with sessile serrated adenomas

A Teriaky, DK Driman, N Chande - Scandinavian journal of …, 2012 - Taylor & Francis
Abstract Objective. Sessile serrated adenomas (SSAs) are precursors to colorectal cancer
(CRC). The purpose of this study is to determine the occurrence of new polyps and CRC in …

[HTML][HTML] Proximal colon cancers and the serrated pathway: a systematic analysis of precursor histology and BRAF mutation status

DT Patil, BL Shadrach, LA Rybicki, BH Leach, RK Pai - Modern Pathology, 2012 - Elsevier
Although the serrated neoplasia pathway is thought to give rise to the majority of sporadic
microsatellite instability-high (MSI-H) colon cancer, the exact proportion of these tumors that …

[HTML][HTML] Cancer stem cells in colorectal cancer: genetic and epigenetic changes

S Roy, APN Majumdar - Journal of stem cell research & therapy, 2012 - ncbi.nlm.nih.gov
Colorectal cancer (CRC), an age-related disease, is the third most common cancer in the
world. Although sporadic CRC, that affects 80–85% of CRC patients, is a multi-step process …

Label-free imaging of basement membranes differentiates normal, precancerous, and cancerous colonic tissues by second-harmonic generation microscopy

S Zhuo, J Yan, G Chen, H Shi, X Zhu, J Lu, J Chen… - PLoS …, 2012 - journals.plos.org
Since changes in the basement membranes are the critical indicators for differentiating
normal, precancerous, and cancerous colonic tissues, direct visualization of these warning …

Increased serum sTRAIL levels were correlated with survival in bevacizumab-treated metastatic colon cancer

A Bisgin, A Kargi, AD Yalcin, C Aydin, D Ekinci… - BMC cancer, 2012 - Springer
Background Colorectal cancer is the third most common cancer and the third leading cause
of cancer-related death. Bevacizumab is a humanized monoclonal antibody developed …

Serrated polyps: new classifications highlight clinical importance

CA Messick, J Church, A Bennett… - Colorectal …, 2012 - Wiley Online Library
Aim Many lesions previously classified as hyperplastic polyps and therefore thought to be
innocuous have been reclassified as sessile serrated adenomas/polyps (SSA/Ps) …

Genetic variants within ultraconserved elements and susceptibility to right-and left-sided colorectal adenocarcinoma

M Lin, C Eng, ET Hawk, M Huang, AJ Greisinger… - …, 2012 - academic.oup.com
We investigated whether single nucleotide polymorphisms within ultraconserved elements
(UCEs) are associated with susceptibility to overall colorectal cancer (CRC) and …