Engineering microscale topographies to control the cell–substrate interface

M Nikkhah, F Edalat, S Manoucheri, A Khademhosseini - Biomaterials, 2012 - Elsevier
Cells in their in vivo microenvironment constantly encounter and respond to a multitude of
signals. While the role of biochemical signals has long been appreciated, the importance of …

Synthesis, properties and biomedical applications of poly (glycerol sebacate)(PGS): A review

R Rai, M Tallawi, A Grigore, AR Boccaccini - Progress in polymer science, 2012 - Elsevier
Poly (glycerol sebacate)(PGS) is a biodegradable polymer increasingly used in a variety of
biomedical applications. This polyester is prepared by polycondensation of glycerol and …

Microfabrication of complex porous tissue engineering scaffolds using 3D projection stereolithography

R Gauvin, YC Chen, JW Lee, P Soman, P Zorlutuna… - Biomaterials, 2012 - Elsevier
The success of tissue engineering will rely on the ability to generate complex, cell seeded
three-dimensional (3D) structures. Therefore, methods that can be used to precisely …

Macroporous nanowire nanoelectronic scaffolds for synthetic tissues

B Tian, J Liu, T Dvir, L Jin, JH Tsui, Q Qing, Z Suo… - Nature materials, 2012 - nature.com
The development of three-dimensional (3D) synthetic biomaterials as structural and
bioactive scaffolds is central to fields ranging from cellular biophysics to regenerative …

Biomimetic scaffolds for tissue engineering

TG Kim, H Shin, DW Lim - Advanced Functional Materials, 2012 - Wiley Online Library
Biomimetic scaffolds mimic important features of the extracellular matrix (ECM) architecture
and can be finely controlled at the nano‐or microscale for tissue engineering. Rational …

Investigating the morphological, mechanical and degradation properties of scaffolds comprising collagen, gelatin and elastin for use in soft tissue engineering

CN Grover, RE Cameron, SM Best - Journal of the mechanical behavior of …, 2012 - Elsevier
Collagen-based scaffolds can be used to mimic the extracellular matrix (ECM) of soft tissues
and provide support during tissue regeneration. To better match the native ECM composition …

Engineering of micro‐and nanostructured surfaces with anisotropic geometries and properties

S Tawfick, M De Volder, D Copic, SJ Park… - Advanced …, 2012 - Wiley Online Library
Widespread approaches to fabricate surfaces with robust micro‐and nanostructured
topographies have been stimulated by opportunities to enhance interface performance by …

Biomaterial strategies for alleviation of myocardial infarction

JR Venugopal, MP Prabhakaran… - Journal of the …, 2012 - royalsocietypublishing.org
World Health Organization estimated that heart failure initiated by coronary artery disease
and myocardial infarction (MI) leads to 29 per cent of deaths worldwide. Heart failure is one …

Synthesis, preparation, in vitro degradation, and application of novel degradable bioelastomers—A review

Q Liu, L Jiang, R Shi, L Zhang - Progress in polymer science, 2012 - Elsevier
Degradable bioelastomers are novel polymer biomaterials mainly applied in soft tissue
engineering and drug delivery. Synthetic degradable bioelastomers present four remarkable …

Biomimetic perfusion and electrical stimulation applied in concert improved the assembly of engineered cardiac tissue

R Maidhof, N Tandon, EJ Lee, J Luo… - Journal of tissue …, 2012 - Wiley Online Library
Maintenance of normal myocardial function depends intimately on synchronous tissue
contraction, driven by electrical activation and on adequate nutrient perfusion in support …