Essential oils in food preservation: mode of action, synergies, and interactions with food matrix components

M Hyldgaard, T Mygind, RL Meyer - Frontiers in microbiology, 2012 - frontiersin.org
Essential oils are aromatic and volatile liquids extracted from plants. The chemicals in
essential oils are secondary metabolites, which play an important role in plant defense as …

Designing antimicrobial peptides: form follows function

CD Fjell, JA Hiss, REW Hancock… - Nature reviews Drug …, 2012 - nature.com
Multidrug-resistant bacteria are a severe threat to public health. Conventional antibiotics are
becoming increasingly ineffective as a result of resistance, and it is imperative to find new …

Neutrophil function: from mechanisms to disease

B Amulic, C Cazalet, GL Hayes… - Annual review of …, 2012 - annualreviews.org
Neutrophils are the most abundant white blood cells in circulation, and patients with
congenital neutrophil deficiencies suffer from severe infections that are often fatal …

Role of lipids in the interaction of antimicrobial peptides with membranes

V Teixeira, MJ Feio, M Bastos - Progress in lipid research, 2012 - Elsevier
Antimicrobial peptides (AMPs) take part in the immune system by mounting a first line of
defense against pathogens. Recurrent structural and functional aspects are observed …

α‐Defensins in human innate immunity

RI Lehrer, W Lu - Immunological reviews, 2012 - Wiley Online Library
Defensins are small, multifunctional cationic peptides. They typically contain six conserved
cysteines whose three intramolecular disulfides stabilize a largely β‐sheet structure. This …

β-Defensins: multifunctional modulators of infection, inflammation and more?

F Semple, JR Dorin - Journal of innate immunity, 2012 - karger.com
Defensins comprise one of the largest groups of host defence peptides, present throughout
evolution, in fungi and flowering plants as well as in invertebrates and vertebrates. These …

Quaternary ammonium salts and their antimicrobial potential: targets or nonspecific interactions?

M Tischer, G Pradel, K Ohlsen, U Holzgrabe - ChemMedChem, 2012 - Wiley Online Library
For more than 50 years dequalinium chloride has been used successfully as an antiseptic
drug and disinfectant, particularly for clinical purposes. Given the success of dequalinium …

Structural perspective of peptidoglycan biosynthesis and assembly

AL Lovering, SS Safadi… - Annual review of …, 2012 - annualreviews.org
The peptidoglycan biosynthetic pathway is a critical process in the bacterial cell and is
exploited as a target for the design of antibiotics. This pathway culminates in the production …

Therapeutic potential of host defense peptides in antibiotic-resistant infections

NJ Afacan, A TY Yeung, OM Pena… - Current …, 2012 - ingentaconnect.com
The emergence of infections caused by multi-drug resistant (MDR) pathogens pose a major
burden to modern healthcare. Exacerbating this issue is the substantial decline in …

Antibacterial and cell-adhesive polypeptide and poly (ethylene glycol) hydrogel as a potential scaffold for wound healing

A Song, AA Rane, KL Christman - Acta biomaterialia, 2012 - Elsevier
The ideal wound-healing scaffold should provide the appropriate physical and mechanical
properties to prevent secondary infection, as well as an excellent physiological environment …