Essential oils in food preservation: mode of action, synergies, and interactions with food matrix components
Essential oils are aromatic and volatile liquids extracted from plants. The chemicals in
essential oils are secondary metabolites, which play an important role in plant defense as …
essential oils are secondary metabolites, which play an important role in plant defense as …
Designing antimicrobial peptides: form follows function
CD Fjell, JA Hiss, REW Hancock… - Nature reviews Drug …, 2012 - nature.com
Multidrug-resistant bacteria are a severe threat to public health. Conventional antibiotics are
becoming increasingly ineffective as a result of resistance, and it is imperative to find new …
becoming increasingly ineffective as a result of resistance, and it is imperative to find new …
Neutrophil function: from mechanisms to disease
B Amulic, C Cazalet, GL Hayes… - Annual review of …, 2012 - annualreviews.org
Neutrophils are the most abundant white blood cells in circulation, and patients with
congenital neutrophil deficiencies suffer from severe infections that are often fatal …
congenital neutrophil deficiencies suffer from severe infections that are often fatal …
Role of lipids in the interaction of antimicrobial peptides with membranes
V Teixeira, MJ Feio, M Bastos - Progress in lipid research, 2012 - Elsevier
Antimicrobial peptides (AMPs) take part in the immune system by mounting a first line of
defense against pathogens. Recurrent structural and functional aspects are observed …
defense against pathogens. Recurrent structural and functional aspects are observed …
α‐Defensins in human innate immunity
Defensins are small, multifunctional cationic peptides. They typically contain six conserved
cysteines whose three intramolecular disulfides stabilize a largely β‐sheet structure. This …
cysteines whose three intramolecular disulfides stabilize a largely β‐sheet structure. This …
β-Defensins: multifunctional modulators of infection, inflammation and more?
F Semple, JR Dorin - Journal of innate immunity, 2012 - karger.com
Defensins comprise one of the largest groups of host defence peptides, present throughout
evolution, in fungi and flowering plants as well as in invertebrates and vertebrates. These …
evolution, in fungi and flowering plants as well as in invertebrates and vertebrates. These …
Quaternary ammonium salts and their antimicrobial potential: targets or nonspecific interactions?
M Tischer, G Pradel, K Ohlsen, U Holzgrabe - ChemMedChem, 2012 - Wiley Online Library
For more than 50 years dequalinium chloride has been used successfully as an antiseptic
drug and disinfectant, particularly for clinical purposes. Given the success of dequalinium …
drug and disinfectant, particularly for clinical purposes. Given the success of dequalinium …
Structural perspective of peptidoglycan biosynthesis and assembly
AL Lovering, SS Safadi… - Annual review of …, 2012 - annualreviews.org
The peptidoglycan biosynthetic pathway is a critical process in the bacterial cell and is
exploited as a target for the design of antibiotics. This pathway culminates in the production …
exploited as a target for the design of antibiotics. This pathway culminates in the production …
Therapeutic potential of host defense peptides in antibiotic-resistant infections
NJ Afacan, A TY Yeung, OM Pena… - Current …, 2012 - ingentaconnect.com
The emergence of infections caused by multi-drug resistant (MDR) pathogens pose a major
burden to modern healthcare. Exacerbating this issue is the substantial decline in …
burden to modern healthcare. Exacerbating this issue is the substantial decline in …
Antibacterial and cell-adhesive polypeptide and poly (ethylene glycol) hydrogel as a potential scaffold for wound healing
A Song, AA Rane, KL Christman - Acta biomaterialia, 2012 - Elsevier
The ideal wound-healing scaffold should provide the appropriate physical and mechanical
properties to prevent secondary infection, as well as an excellent physiological environment …
properties to prevent secondary infection, as well as an excellent physiological environment …