[HTML][HTML] Identification of a radiosensitivity signature using integrative metaanalysis of published microarray data for NCI-60 cancer cells

HS Kim, SC Kim, SJ Kim, CH Park, HC Jeung, YB Kim… - BMC genomics, 2012 - Springer
Background In the postgenome era, a prediction of response to treatment could lead to
better dose selection for patients in radiotherapy. To identify a radiosensitive gene signature …

[HTML][HTML] Network methods for describing sample relationships in genomic datasets: application to Huntington's disease

MC Oldham, P Langfelder, S Horvath - BMC systems biology, 2012 - Springer
Background Genomic datasets generated by new technologies are increasingly prevalent in
disparate areas of biological research. While many studies have sought to characterize …

ARSyN: a method for the identification and removal of systematic noise in multifactorial time course microarray experiments

MJ Nueda, A Ferrer, A Conesa - Biostatistics, 2012 - academic.oup.com
Transcriptomic profiling experiments that aim to the identification of responsive genes in
specific biological conditions are commonly set up under defined experimental designs that …

[HTML][HTML] Batch correction of microarray data substantially improves the identification of genes differentially expressed in rheumatoid arthritis and osteoarthritis

P Kupfer, R Guthke, D Pohlers, R Huber… - BMC medical …, 2012 - Springer
Background Batch effects due to sample preparation or array variation (type, charge, and/or
platform) may influence the results of microarray experiments and thus mask and/or …

Batch effects correction improves the sensitivity of significance tests in spectral counting-based comparative discovery proteomics

J Gregori, L Villarreal, O Méndez, A Sánchez… - Journal of …, 2012 - Elsevier
Shotgun proteomics has become the standard proteomics technique for the large-scale
measurement of protein abundances in biological samples. Despite quantitative proteomics …

[HTML][HTML] G-cimp status prediction of glioblastoma samples using mRNA expression data

M Baysan, S Bozdag, MC Cam, S Kotliarova, S Ahn… - PloS one, 2012 - journals.plos.org
Glioblastoma Multiforme (GBM) is a tumor with high mortality and no known cure. The
dramatic molecular and clinical heterogeneity seen in this tumor has led to attempts to …

Derivation and validation of a cytokine-based assay to screen for acute rejection in renal transplant recipients

SA De Serres, BG Mfarrej, M Grafals… - Clinical Journal of the …, 2012 - journals.lww.com
Results Although six cytokines (IL-1β, IL-6, TNF-α, IL-4, GM-CSF, and monocyte
chemoattractant protein-1) distinguished acute rejectors in the training cohort, logistic …

The practical effect of batch on genomic prediction

HS Parker, JT Leek - … applications in genetics and molecular biology, 2012 - degruyter.com
Measurements from microarrays and other high-throughput technologies are susceptible to
non-biological artifacts like batch effects. It is known that batch effects can alter or obscure …

[HTML][HTML] Four new SYBR®Green qPCR screening methods for the detection of Roundup Ready®, LibertyLink®, and CryIAb traits in genetically modified products

E Barbau-Piednoir, A Lievens, E Vandermassen… - … Food Research and …, 2012 - Springer
SYBR® Green qPCR methods for the detection of the Roundup Ready®“CP4-EPSPS”,
LibertyLink®“PAT” and “BAR,” and the Bacillus thuringiensis “CryIAb” traits as present in …

Reverse engineering biomolecular systems using− omic data: challenges, progress and opportunities

CF Quo, C Kaddi, JH Phan, A Zollanvari… - Briefings in …, 2012 - academic.oup.com
Recent advances in high-throughput biotechnologies have led to the rapid growing research
interest in reverse engineering of biomolecular systems (REBMS).'Data-driven'approaches …