Mammalian reproduction hinges upon the timely ovulation of a fully differentiated oocyte.
This event is the culmination of a complex and dynamic developmental relationship between …

Contents Progesterone is critical for successful ovulation in the ovary and for the multi‐
faceted role of the oviduct in mammalian reproduction. Its effects are mediated by …

Ovulation, the release of the oocyte from the ovarian follicle, is initiated by the luteinizing
hormone surge. It is clear that highly controlled degradation of the follicle and ovarian wall is …

Steroid hormones coordinate and control the development and function of many organs and
are implicated in many pathological processes. Progesterone signaling, in particular, is …

While formation of the expanded cumulus matrix and its importance for oocyte maturation
and ovulation are well described, its function in these processes remains unknown. The …

The Vaccinia-related kinase 1 (VRK1), which is generally implicated in modulating cell
cycle, plays important roles in mammalian gametogenesis. Female infertility in VRK1 …

In this study, we report for the first time on a possible contribution of metalloproteases in
sperm passage through the cumulus matrix in pigs. The presence of 20 mM 1, 10 …

Abstract Changes in gene expression during development play an important role in shaping
morphological and behavioral differences, including between humans and nonhuman …

The hyalectan family of extracellular matrix (ECM) chondroitin sulphate proteoglycans
comprises aggrecan, brevican, neurocan and versican. Although they share common …

Angiogenesis is essential for embryonic development, growth and adult physiology. It is also
critical in various pathological conditions such as cancer, rheumatoid arthritis and diabetic …