Muscarinic receptor pharmacology and circuitry for the modulation of cognition
The muscarinic cholinergic system constitutes an important part of the neuronal circuitry that
modulates normal cognition. Muscarinic receptor antagonists are well known to produce or …
modulates normal cognition. Muscarinic receptor antagonists are well known to produce or …
Muscarinic mechanisms in psychotic disorders
DL McKinzie, FP Bymaster - Novel Antischizophrenia Treatments, 2012 - Springer
Schizophrenia is a devastating disease with several broad symptom clusters and the current
monoamine-based treatments do not adequately treat the disease, especially negative and …
monoamine-based treatments do not adequately treat the disease, especially negative and …
Muscarinic receptor/G-protein coupling is reduced in the dorsomedial striatum of cognitively impaired aged rats
E Nieves-Martinez, K Haynes, SR Childers… - Behavioural brain …, 2012 - Elsevier
Behavioral flexibility, the ability to modify responses due to changing task demands, is
detrimentally affected by aging with a shift towards increased cognitive rigidity. The …
detrimentally affected by aging with a shift towards increased cognitive rigidity. The …
Acetylcholine from the mesopontine tegmental nuclei differentially affects methamphetamine induced locomotor activity and neurotransmitter levels in the mesolimbic …
LK Dobbs, GP Mark - Behavioural brain research, 2012 - Elsevier
Methamphetamine (MA) increases dopamine (DA) levels within the mesolimbic pathway
and acetylcholine (ACh), a neurotransmitter known to increase DA cell firing and release …
and acetylcholine (ACh), a neurotransmitter known to increase DA cell firing and release …