Pre-rheumatoid arthritis: predisposition and transition to clinical synovitis

WP Arend, GS Firestein - Nature Reviews Rheumatology, 2012 - nature.com
Multiple proven and potential risk factors for the development of rheumatoid arthritis (RA)
have been identified, and represent interactions between genes and the environment …

MicroRNAs in rheumatoid arthritis: potential role in diagnosis and therapy

M Filková, A Jüngel, RE Gay, S Gay - BioDrugs, 2012 - Springer
Rheumatoid arthritis (RA) is a systemic, inflammatory, autoimmune disorder with progressive
articular damage that may result in lifelong disability. Although major strides in …

MicroRNAs and autoimmunity

A Ceribelli, M Satoh, EKL Chan - Current opinion in immunology, 2012 - Elsevier
The role of microRNAs (miRNAs) in the regulation of many physiological and pathological
processes has been intensely studied in recent years. Some miRNAs, such as miR-146a …

Epigenetic contributions in the development of rheumatoid arthritis

K Klein, C Ospelt, S Gay - Arthritis Research & Therapy, 2012 - Springer
Rheumatoid arthritis (RA) is an autoimmune disease, characterized by chronic inflammation
of the joints with severe pain and swelling, joint damage and disability, which leads to joint …

Epigenetics Changes in the RA Synovium

C Ospelt - Current Rheumatology Reviews, 2012 - ingentaconnect.com
The fast technological progress of bio-medical research in the last decade led to the
accumulation of vast amounts of data and opened new fields of research, such as …

関節とmicroRNA

田中陽子, 浅原弘嗣 - 日本臨床免疫学会会誌, 2012 - jstage.jst.go.jp
抄録 MicroRNA (miRNA) は生物の発生やガンをはじめとした様々な疾患に関与していることが
明らかになってきている. タンパク質の遺伝子配列をもたない Small RNA に RNA …

関節リウマチにおけるmicroRNA の役割

溝口史高, 上阪 - 日本臨床免疫学会会誌, 2012 - jstage.jst.go.jp
抄録 近年様々な生理的・病的状態における microRNA の役割が明らかになってきている.
特に免疫における microRNA の役割については詳細な検討が進められている …

[引用][C] miRNA functions in arthritis

S Yamashita, H Asahara - Current Rheumatology Reviews, 2012 - ingentaconnect.com
MicroRNAs (miRNAs) are classes of non-coding RNA that function as negative regulators of
protein-coding gene expression at the post-transcription level. It has been elucidated that …