Epigenetic phenomena in animals and plants are mediated by DNA methylation and stable
chromatin modifications. There has been considerable interest in whether environmental …

It is known that information that is not contained in the DNA sequence—epigenetic
information—can be inherited from the parent to the offspring. However, many questions …

The modification of DNA by 5-methylcytosine (5mC) has essential roles in cell differentiation
and development through epigenetic gene regulation. 5mC can be converted to another …

The once popular and then heretical idea that ancestral environment can affect the
phenotype of future generations is coming back into vogue due to advances in the field of …

Histone modifications influence the interactions of transcriptional regulators with chromatin.
Studies in embryos and embryonic stem (ES) cells have uncovered histone modification …

DNA methylation has been comprehensively profiled in normal and cancer cells, but the
dynamics that form, maintain and reprogram differentially methylated regions remain …

The science of genetics is undergoing a paradigm shift. Recent discoveries, including the
activity of retrotransposons, the extent of copy number variations, somatic and chromosomal …

Recent work in the field of male fertility has yielded significant increases in our
understanding of the sperm epigenome and its potential role in embryonic development …

BACKGROUND The subject of epigenetic risk of assisted reproduction treatment (ART),
initiated by reports on an increase of children with the Beckwith–Wiedemann imprinting …

Enhancers are regulatory DNA elements that dictate the spatial and temporal patterns of
gene expression during development. Recent evidence suggests that the distinct chromatin …