Overcoming poor oral bioavailability using nanoparticle formulations–opportunities and limitations
Oral delivery of drugs with poor aqueous solubility and poor enzymatic and/or metabolic
stability is very challenging. However, the advent of nanotechnology has revolutionized the …
stability is very challenging. However, the advent of nanotechnology has revolutionized the …
Improved dissolution and pharmacokinetic behavior of dipyridamole formulation with microenvironmental pH-modifier under hypochlorhydria
S Onoue, R Inoue, C Taniguchi, Y Kawabata… - International journal of …, 2012 - Elsevier
The present study aimed to develop and characterize new formulations of dipyridamole
(DP), a pH-dependent poorly soluble drug, employing an acidic pH-modifier for improving …
(DP), a pH-dependent poorly soluble drug, employing an acidic pH-modifier for improving …
CriticalSorb™ promotes permeation of flux markers across isolated rat intestinal mucosae and Caco-2 monolayers
Purpose CriticalSorb™ is a novel absorption enhancer based on Solutol® HS15, one that
has been found to enhance the nasal transport. It is in clinical trials for nasal delivery of …
has been found to enhance the nasal transport. It is in clinical trials for nasal delivery of …
星点设计-效应面法优化葛根素自微乳化释药系统
江兴龙， 贾运涛， 张良珂， 田睿， 滕永真 - 第三军医大学学报, 2012 - cqvip.com
目的葛根素自微乳化释药系统的制备优化及评价. 方法通过测定葛根素在各辅料中的溶解度,
处方配伍实验, 绘制伪三元相图筛选自微乳化释药系统组分; 以葛根素在不同自微乳处方中的 …
处方配伍实验, 绘制伪三元相图筛选自微乳化释药系统组分; 以葛根素在不同自微乳处方中的 …
[图书][B] Salt solid dispersions: a formulation strategy to enhance dissolution rate of poorly water-soluble ionic drugs
AA Ghosh - 2012 - search.proquest.com
Improving oral bioavailability of poorly water-soluble drugs remains one of the most
challenging aspects of drug development. Pharmaceutical salt formation is a widely …
challenging aspects of drug development. Pharmaceutical salt formation is a widely …
Study of formation self-nanoemulsifying systems, containing cationic peptide derivatives
OO Koloskova, AM Sumina, KI Kononova… - …, 2012 - elibrary.ru
Studies on production and properties of cationic submicron emulsions o/w, containing
lipopeptides as delivery systems for biologically active substances were carried out. In the …
lipopeptides as delivery systems for biologically active substances were carried out. In the …