NADPH oxidases of the NADPH oxidase (NOX) family are dedicated reactive oxygen
species-generating enzymes that broadly and specifically regulate redox-sensitive …

Oxidative stress is a molecular dysregulation in reactive oxygen species (ROS) metabolism,
which plays a key role in the pathogenesis of atherosclerosis, vascular inflammation and …

The classical nicotinamide adenine dinucleotide phosphate (NADPH) oxidase was
originally detected in neutrophils as a multicomponent enzyme that catalyzes the generation …

Reactive oxygen species (ROS) act physiologically as signaling molecules. In pathological
conditions, such as ischemic stroke, ROS are released in excessive amounts and upon …

Influenza A viral infections claim millions of lives worldwide and continue to impose a major
burden on healthcare systems. Current pharmacological strategies to control influenza A …

In mammals, the NADPH oxidase family of enzymes comprises seven members: NOXs 1–5,
DUOX1, and DUOX2. All of these enzymes function to move an electron across cellular …

NADPH oxidases (Nox) are established as major sources of reactive oxygen species (ROS).
Over the past two decades, Nox-derived ROS have emerged as pivotal in the development …

Significance: Reactive oxygen species (ROS) such as superoxide, hydrogen peroxide, and
peroxynitrite are generated ubiquitously by all mammalian cells and have been understood …

Mitochondria play a fundamental role in the maintenance of normal structure, function, and
survival of tissues. There is considerable evidence for mitochondrial dysfunction in …

It is well-known that insulin acts as an important hormone, controlling energy metabolism,
cellular proliferation and biosynthesis of functional molecules to maintain a biological …