From the first measurements of the distribution of pulmonary blood flow using radioactive
tracers by West and colleagues (J Clin Invest 40: 1–12, 1961) allowing gravitational …

This exceptional book is concerned with the application of fractals and chaos, as well as
other concepts from nonlinear dynamics to biomedical phenomena. Herein we seek to …

Dead space is the portion of a tidal volume that does not participate in gas exchange
because it does not get in contact with blood flowing through the pulmonary capillaries. It is …

The topographic distribution of ventilation in the lungs is determined by the interaction of
several factors, including lung shape, airway tree geometry, posture, and tissue deformation …

The role of imaging as a tool for investigating lung physiology is growing at an accelerating
pace. Looking forward, we wished to identify unresolved issues in lung physiology that might …

A mathematical principle is an overarching statement of what will always occur given a
prescribed set of circumstances. Such principles are very useful because they can guide us …

Pulmonary diseases are characterized by small-scale and large-scale alterations in
structure and function of the lung. Multidetector-row computed tomography (MDCT) is a …