Histamine-releasing and allergenic properties of opioid analgesic drugs: resolving the two
BA Baldo, NH Pham - Anaesthesia and intensive care, 2012 - journals.sagepub.com
Opioid analgesics are amongst the most commonly administered drugs in hospitals.
Whether natural or synthetic, they show some common structural features, morphine-like …
Whether natural or synthetic, they show some common structural features, morphine-like …
Histamine H3 receptor antagonists in relation to epilepsy and neurodegeneration: a systemic consideration of recent progress and perspectives
M Bhowmik, R Khanam… - British journal of …, 2012 - Wiley Online Library
The central histaminergic actions are mediated by H1, H2, H3 and H4 receptors. The
histamine H3 receptor regulates the release of histamine and a number of other …
histamine H3 receptor regulates the release of histamine and a number of other …
Synthesis, biological evaluation and SAR studies of benzimidazole derivatives as H1-antihistamine agents
XJ Wang, MY Xi, JH Fu, FR Zhang, GF Cheng… - Chinese Chemical …, 2012 - Elsevier
A series of benzimidazole derivatives have been designed, synthesized and evaluated for
H1 antihistamine activity. Six compounds have showed potent antihistamine H1 activity. The …
H1 antihistamine activity. Six compounds have showed potent antihistamine H1 activity. The …
Incomplete activation of human eosinophils via the histamine H4-receptor: evidence for ligand-specific receptor conformations
TM Reher, D Neumann, A Buschauer… - Biochemical pharmacology, 2012 - Elsevier
Eosinophils play a crucial role in the pathogenesis of allergic diseases. Histamine activates
eosinophils via the H4-receptor (H4R). However, pharmacological analysis of the H4R in …
eosinophils via the H4-receptor (H4R). However, pharmacological analysis of the H4R in …
Commercially available antibodies against human and murine histamine H4-receptor lack specificity
S Beermann, R Seifert, D Neumann - Naunyn-Schmiedeberg's archives of …, 2012 - Springer
Antibodies are important tools to detect expression and localization of proteins within the
living cell. However, for a series of commercially available antibodies which are supposed to …
living cell. However, for a series of commercially available antibodies which are supposed to …
[PDF][PDF] Histamine receptor subtypes: a century of rational drug design
M Walter, H Stark - Frontiers in Bioscience-Scholar, 2012 - academia.edu
Introduction 3. Histamine H1 receptor 3.1. Histamine H1 receptor agonists 3.2. Histamine H1
receptor antagonists 4. Histamine H2 receptor 4.1. Histamine H2 receptor agonists 4.2 …
receptor antagonists 4. Histamine H2 receptor 4.1. Histamine H2 receptor agonists 4.2 …
[HTML][HTML] Histamine and histamine receptor regulation of gastrointestinal cancers
L Kennedy, K Hodges, F Meng, G Alpini… - Translational …, 2012 - ncbi.nlm.nih.gov
Histamine is a neurotransmitter released throughout the body that regulates multiple
physiological responses. Primarily histamine is acknowledged for its role in inflammatory …
physiological responses. Primarily histamine is acknowledged for its role in inflammatory …
A novel fluorescent histamine H1 receptor antagonist demonstrates the advantage of using fluorescence correlation spectroscopy to study the binding of lipophilic …
RH Rose, SJ Briddon, SJ Hill - British journal of pharmacology, 2012 - Wiley Online Library
BACKGROUND AND PURPOSE Fluorescent ligands facilitate the study of ligand–receptor
interactions at the level of single cells and individual receptors. Here, we describe a novel …
interactions at the level of single cells and individual receptors. Here, we describe a novel …
Interactions of recombinant human histamine H1, H2, H3, and H4 receptors with 34 antidepressants and antipsychotics
H Appl, T Holzammer, S Dove, E Haen… - Naunyn-Schmiedeberg's …, 2012 - Springer
Antidepressants and antipsychotics affect multiple molecular targets. Consequently, these
drugs exhibit not only unique profiles of therapeutic effects but also several undesired …
drugs exhibit not only unique profiles of therapeutic effects but also several undesired …
Histamine is a modulator of metamorphic competence in Strongylocentrotus purpuratus(Echinodermata: Echinoidea)
J Sutherby, JL Giardini, J Nguyen, G Wessel… - BMC developmental …, 2012 - Springer
Background A metamorphic life-history is present in the majority of animal phyla. This
developmental mode is particularly prominent among marine invertebrates with a bentho …
developmental mode is particularly prominent among marine invertebrates with a bentho …