Primary ovarian insufficiency (POI), also known as premature ovarian failure, is a disorder of
infertility characterized by amenorrhoea, low estrogen levels and increased gonadotropin …

The human luteinizing hormone/chorionic gonadotropin receptor (LHCGR) plays a
fundamental role in male and female reproductive physiology. Over the past 15 years …

Objective Polycystic ovary syndrome (PCOS) is a frequent condition, affecting about 15% of
women of reproductive age. Because of its familial occurrence, a multifactorial model of …

Context: LH gene mutations are rare; only four mutations have been described. The affected
individuals are hypogonadal. Patient: We describe the clinical features of a 31-yr-old man …

OBJECTIVE: To study the cause for poor oocyte yield, amenorrhea, and recurrent pregnancy
loss in a patient undergoing IVF. DESIGN: Case report. SETTING: University-affiliated …

Since puberty is a long ongoing developmental process with significant individual and
population differences in timing, the definition of delayed puberty for a given individual …

OBJECTIVE: To identify whether epistasis between TG and HSD17B4 and whether
polymorphisms in HSD17B4 are associated with premature ovarian failure (POF). DESIGN …

Publisher Summary This chapter reviews the molecular basis of reproductive disorders in
the human, including those that result in hypogonadism as well as eugonadism along with …

on bone formation in mice, suggesting a connection between the gut and bone. Sjögren and
colleagues set out to investigate the effect of the gut microbiota on bone mass in mice. The …

Abstract The Genes Involved in Hearing and Endocrine Disorders. Emma Mary Jenkinson,
the University of Manchester, PhD in Developmental Biomedicine, submitted 2012In recent …