How mesenchymal stem cells interact with tissue immune responses

Y Shi, J Su, AI Roberts, P Shou, AB Rabson… - Trends in immunology, 2012 - cell.com
Mesenchymal stem cells (MSCs), also called multipotent mesenchymal stromal cells, exist in
almost all tissues and are a key cell source for tissue repair and regeneration. Under …

The immunomodulatory and neuroprotective effects of mesenchymal stem cells (MSCs) in experimental autoimmune encephalomyelitis (EAE): a model of multiple …

MA Al Jumah, MH Abumaree - International journal of molecular sciences, 2012 - mdpi.com
Mesenchymal stem cells (MSCs) are multipotent cells that differentiate into the
mesenchymal lineages of adipocytes, osteocytes and chondrocytes. MSCs can also …

Hepatocyte growth factor mediates mesenchymal stem cell–induced recovery in multiple sclerosis models

L Bai, DP Lennon, AI Caplan, A DeChant… - Nature …, 2012 - nature.com
Mesenchymal stem cells (MSCs) have emerged as a potential therapy for a range of neural
insults. In animal models of multiple sclerosis, an autoimmune disease that targets …

Immunogenicity of allogeneic mesenchymal stem cells

S Schu, M Nosov, L O'Flynn, G Shaw… - Journal of cellular …, 2012 - Wiley Online Library
Mesenchymal stem cells (MSCs) inhibit proliferation of allogeneic T cells and express low
levels of major histocompatibility complex class I (MHCI), MHCII and vascular adhesion …

Early intervention with gene-modified mesenchymal stem cells overexpressing interleukin-4 enhances anti-inflammatory responses and functional recovery in …

NL Payne, A Dantanarayana, G Sun… - Cell adhesion & …, 2012 - Taylor & Francis
Mesenchymal stem/stromal cells (MSCs) can be isolated from most adult tissues and hold
considerable promise for tissue regenerative therapies. Some of the potential advantages …

[HTML][HTML] Adult mesenchymal stem cell therapy for myelin repair in multiple sclerosis

FJ Rivera, L Aigner - Biological research, 2012 - SciELO Chile
Multiple sclerosis (MS) is a demyelinating immune-mediated disease of the central nervous
system (CNS). It is the most frequent neurological disease in young adults and affects over 2 …

Therapeutic potential of mesenchymal stem cells for oral and systemic diseases

RH Kim, S Mehrazarin, MK Kang - Dental Clinics of North America, 2012 - Elsevier
Mesenchymal stem cells (MSCs) are adult stem cells whose self-renewal, multipotency, and
immunosuppressive functions have been investigated for therapeutic applications. MSCs …

The remyelination Philosopher's Stone: stem and progenitor cell therapies for multiple sclerosis

JJ Jadasz, L Aigner, FJ Rivera, P Küry - Cell and tissue research, 2012 - Springer
Multiple sclerosis (MS) is an autoimmune disease that leads to oligodendrocyte loss and
subsequent demyelination of the adult central nervous system (CNS). The pathology is …

Nonclinical safety strategies for stem cell therapies

ME Sharpe, D Morton, A Rossi - Toxicology and applied pharmacology, 2012 - Elsevier
Recent breakthroughs in stem cell biology, especially the development of the induced
pluripotent stem cell techniques, have generated tremendous enthusiasm and efforts to …

Mesenchymal stromal cells for tissue‐engineered tissue and organ replacements

S Baiguera, P Jungebluth, B Mazzanti… - Transplant …, 2012 - Wiley Online Library
Mesenchymal stromal cells (MSCs), a rare heterogeneous subset of pluripotent stromal cells
that can be easily isolated from different adult tissues, in vitro expanded and differentiated …