Curcumin—from molecule to biological function

T Esatbeyoglu, P Huebbe, IMA Ernst… - Angewandte Chemie …, 2012 - Wiley Online Library
Turmeric is traditionally used as a spice and coloring in foods. It is an important ingredient in
curry and gives curry powder its characteristic yellow color. As a consequence of its intense …

Redox control of cell proliferation

J Chiu, IW Dawes - Trends in cell biology, 2012 - cell.com
Cell proliferation is regulated by multiple signaling pathways and stress surveillance
systems to ensure cell division takes place with fidelity. In response to oxidative stress, cells …

Nuclear factor-E2-related factor 2 is a major determinant of bile acid homeostasis in the liver and intestine

J Weerachayaphorn, A Mennone… - American Journal …, 2012 - journals.physiology.org
The transcription factor nuclear factor-E2-related factor 2 (Nrf2) is a key regulator for
induction of hepatic detoxification and antioxidant mechanisms, as well as for certain …

Antioxidants in chemistry and biology

L Valgimigli, DA Pratt - … of radicals in chemistry, biology and …, 2012 - Wiley Online Library
Antioxidants are omnipresent in nature and industry; they are used to slow down the
autoxidative degradation of both organic tissues and petroleum‐derived products. Various …

Therapeutic approach to neurodegenerative diseases by medical gases: focusing on redox signaling and related antioxidant enzymes

K Fujita, M Yamafuji, Y Nakabeppu… - Oxidative medicine and …, 2012 - Wiley Online Library
Oxidative stress in the central nervous system is strongly associated with neuronal cell death
in the pathogenesis of several neurodegenerative diseases such as Alzheimer′ s disease …

Toona sinensis Roem leaf extracts improve antioxidant activity in the liver of rats under oxidative stress

WJ Yu, CC Chang, TF Kuo, TC Tsai… - Food and Chemical …, 2012 - Elsevier
Toona sinensis Roem (TS) is an herbal plant widely cultivated in Asia. Recently, several
antioxidant compounds in TS leaf (TSL) extracts were chemically identified including …

The role of sulfhydryl reactivity of small molecules for the activation of the KEAP1/NRF2 pathway and the heat shock response

AT Dinkova-Kostova - Scientifica, 2012 - Wiley Online Library
The KEAP1/NRF2 pathway and the heat shock response are two essential cytoprotective
mechanisms that allow adaptation and survival under conditions of oxidative, electrophilic …

Curcumin–vom Molekül zur biologischen Wirkung

T Esatbeyoglu, P Huebbe, IMA Ernst… - Angewandte …, 2012 - Wiley Online Library
Curcuma (Gelbwurzel) wird traditionell als Würzmittel für Lebensmittel eingesetzt. Curcumin
ist ein wichtiger Bestandteil des Currypulvers und verleiht dem Pulver seine …

Modulation of arsenic-induced epidermal growth factor receptor pathway signalling by resveratrol

KJ Herbert, ET Snow - Chemico-biological interactions, 2012 - Elsevier
Arsenic (As) is both a human carcinogen and an effective anticancer drug. These aspects of
arsenic toxicity develop as a consequence of arsenic-induced oxidative stress and …

Effects of estrogen on endothelial prostanoid production and cyclooxygenase-2 and heme oxygenase-1 expression

E Marcantoni, L Di Francesco, L Totani, A Piccoli… - Prostaglandins & Other …, 2012 - Elsevier
We studied the effects of 17β-estradiol (E2)(10, 40nM) on 2 vasoprotective pathways, ie
cyclooxygenase-2 (COX-2)-dependent prostanoids and the antioxidant heme oxygenase-1 …