Centrosome positioning in vertebrate development
N Tang, WF Marshall - Journal of cell science, 2012 - journals.biologists.com
The centrosome, a major organizer of microtubules, has important functions in regulating
cell shape, polarity, cilia formation and intracellular transport as well as the position of …
cell shape, polarity, cilia formation and intracellular transport as well as the position of …
[PDF][PDF] Positive and negative signaling through SLAM receptors regulate synapse organization and thresholds of cytolysis
F Zhao, JL Cannons, M Dutta, GM Griffiths… - Immunity, 2012 - cell.com
X-linked lymphoproliferative syndrome, characterized by fatal responses to Epstein-Barr
virus infection, is caused by mutations affecting the adaptor SAP, which links SLAM family …
virus infection, is caused by mutations affecting the adaptor SAP, which links SLAM family …
Cytokine secretion by CD4+ T cells at the immunological synapse requires Cdc42-dependent local actin remodeling but not microtubule organizing center polarity
K Chemin, A Bohineust, S Dogniaux… - The Journal of …, 2012 - journals.aai.org
Cytokine secretion by T lymphocytes plays a central role in mounting adaptive immune
responses. However, little is known about how newly synthesized cytokines, once produced …
responses. However, little is known about how newly synthesized cytokines, once produced …
INF2 promotes the formation of detyrosinated microtubules necessary for centrosome reorientation in T cells
L Andrés-Delgado, OM Antón, F Bartolini… - Journal of Cell …, 2012 - rupress.org
T cell antigen receptor–proximal signaling components, Rho-family GTPases, and formin
proteins DIA1 and FMNL1 have been implicated in centrosome reorientation to the …
proteins DIA1 and FMNL1 have been implicated in centrosome reorientation to the …
Cytotoxic T lymphocyte effector function is independent of nucleus–centrosome dissociation
WWY Lui‐Roberts, JC Stinchcombe… - European Journal of …, 2012 - Wiley Online Library
Cytotoxic T lymphocytes (CTL s) kill tumorigenic and virally infected cells by targeted
secretion of lytic granule contents. The precise point at which secretion occurs is directed by …
secretion of lytic granule contents. The precise point at which secretion occurs is directed by …
Role of the MTOC in T cell effector functions
T cells play important roles in defending the host against infections, in allergic responses,
and in the destruction of tumor cells. The directed or focused delivery of effector molecules to …
and in the destruction of tumor cells. The directed or focused delivery of effector molecules to …
Lymphocyte signaling: a Tuscan affair
Lymphocyte signaling: a Tuscan affair | Nature Immunology Skip to main content Thank you for
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visiting nature.com. You are using a browser version with limited support for CSS. To obtain the …