Microfluidics for mammalian cell chemotaxis

BJ Kim, M Wu - Annals of biomedical engineering, 2012 - Springer
The emerging field of micro-technology has opened up new possibilities for exploring
cellular chemotaxis in real space and time, and at single cell resolution. Chemotactic cells …

[HTML][HTML] Physical confinement alters tumor cell adhesion and migration phenotypes

EM Balzer, Z Tong, CD Paul, WC Hung… - The FASEB …, 2012 - ncbi.nlm.nih.gov
Cell migration on planar surfaces is driven by cycles of actin protrusion, integrin-mediated
adhesion, and myosin-mediated contraction; however, this mechanism may not accurately …

Quantifying traction stresses in adherent cells

CM Kraning-Rush, SP Carey, JP Califano… - Methods in Cell …, 2012 - Elsevier
Contractile force generation plays a critical role in cell adhesion, migration, and extracellular
matrix reorganization in both 2D and 3D environments. Characterization of cellular forces …

The effect of injectable gelatin-hydroxyphenylpropionic acid hydrogel matrices on the proliferation, migration, differentiation and oxidative stress resistance of adult …

TC Lim, WS Toh, LS Wang, M Kurisawa, M Spector - Biomaterials, 2012 - Elsevier
Transplanted or endogenous neural stem cells often lack appropriate matrix in cavitary
lesions in the central nervous system. In this study, gelatin-hydroxyphenylpropionic acid (Gtn …

Electrotaxis of lung cancer cells in ordered three-dimensional scaffolds

YS Sun, SW Peng, KH Lin, JY Cheng - Biomicrofluidics, 2012 - pubs.aip.org
In this paper, we report a new method to incorporate 3D scaffold with electrotaxis
measurement in the microfluidic device. The electrotactic response of lung cancer cells in …

Responsive culture platform to examine the influence of microenvironmental geometry on cell function in 3D

AM Kloxin, KJR Lewis, CA DeForest… - Integrative …, 2012 - academic.oup.com
We describe the development of a well-based cell culture platform that enables
experimenters to control the geometry and connectivity of cellular microenvironments …

Characterization of a hierarchical network of hyaluronic acid/gelatin composite for use as a smart injectable biomaterial

HK Heris, M Rahmat, L Mongeau - Macromolecular bioscience, 2012 - Wiley Online Library
Hybrid HA/Ge hydrogel particles are embedded in a secondary HA network to improve their
structural integrity. The internal microstructure of the particles is imaged through TEM. CSLM …

Imaging of cell adhesion events in 3D matrix environments

A Jayo, M Parsons - European journal of cell biology, 2012 - Elsevier
Cell adhesion plays an essential role in development and homeostasis, but is also a key
regulator of many diseases such as cancer and immune dysfunction. Numerous studies over …

Quartz crystal microbalance with dissipation monitoring and the real-time study of biological systems and macromolecules at interfaces

A Ausili, M Berglin, H Elwing… - Biomedical …, 2012 - content.iospress.com
QCM-D technique is based on the physical phenomenon that generates an acoustic shear
wave with an oscillating resonance in quartz resulting in an evanescent wave that arises at …

Characterization and intracellular delivery of MK2-inhibitor peptides for inflammatory applications

JL Brugnano - 2012 - search.proquest.com
The inflammatory response is essential for the body's recovery from injury and infection;
however, chronic inflammation can lead to tissue destruction. Several different diseases …