Inflammation and adaptive immunity in Parkinson's disease
RL Mosley, JA Hutter-Saunders… - Cold Spring …, 2012 - perspectivesinmedicine.cshlp.org
The immune system is designed to protect the host from infection and injury. However, when
an adaptive immune response continues unchecked in the brain, the proinflammatory innate …
an adaptive immune response continues unchecked in the brain, the proinflammatory innate …
Roles of toll-like receptors in cancer: a double-edged sword for defense and offense
Toll-like receptors (TLRs) belong to a class of pattern-recognition receptors that play an
important role in host defense against pathogens by recognizing a wide variety of pathogen …
important role in host defense against pathogens by recognizing a wide variety of pathogen …
Intrinsic danger: activation of Toll-like receptors in rheumatoid arthritis
FG Goh, KS Midwood - Rheumatology, 2012 - academic.oup.com
RA is a debilitating disorder that manifests as chronic localized synovial and systemic
inflammation leading to progressive joint destruction. Recent advances in the molecular …
inflammation leading to progressive joint destruction. Recent advances in the molecular …
Dual role of Toll-like receptors in asthma and chronic obstructive pulmonary disease
GFG Bezemer, S Sagar… - Pharmacological …, 2012 - ASPET
During the last decade, significant research has been focused on Toll-like receptors (TLRs)
in the pathogenesis of airway diseases. TLRs are pattern recognition receptors that play …
in the pathogenesis of airway diseases. TLRs are pattern recognition receptors that play …
Polymorphisms in toll-like receptor 1 and 9 genes and their association with tuberculosis susceptibility in Chinese Holstein cattle
L Sun, Y Song, H Riaz, H Yang, G Hua, A Guo… - Veterinary immunology …, 2012 - Elsevier
Toll-like receptors (TLRs) are a class of pattern recognition receptors that play a pivotal role
in the innate and adaptive immune systems. Studies have shown that TLR variants play …
in the innate and adaptive immune systems. Studies have shown that TLR variants play …
siRNA and cancer immunotherapy
S Ghafouri-Fard, S Ghafouri-Fard - Immunotherapy, 2012 - Taylor & Francis
Immunotherapeutic approaches have been gaining attention in the field of cancer treatment
because of their possible ability to eradicate cancer cells as well as metastases by recruiting …
because of their possible ability to eradicate cancer cells as well as metastases by recruiting …
Mucins and toll-like receptors: kith and kin in infection and cancer
Inflammation is underlying biological phenomenon common in infection and cancer. Mucins
are glycoproteins which establish a physical barrier for undesirable entry of foreign materials …
are glycoproteins which establish a physical barrier for undesirable entry of foreign materials …
Toll-like receptor signalling in liver disease: ER stress the missing link?
MW Lawless, CM Greene - Cytokine, 2012 - Elsevier
Toll-like receptors induce a complex inflammatory response that can function to alert the
body to infection, neutralize pathogens and repair damaged tissues. Toll-like receptors are …
body to infection, neutralize pathogens and repair damaged tissues. Toll-like receptors are …
[PDF][PDF] Systems biological approaches reveal non-additive responses and multiple crosstalk mechanisms between TLR and GPCR signaling
J Krishnan, S Choi - Genomics Inform, 2012 - synapse.koreamed.org
Chemokine (cxc) motif ligand 10a 1.7 NA NM_009845 CD22 antigen 1.7 2.0 NM_009404
Tumor necrosis factor (ligand) superfamily, member 9 1.4 2.1 NM_010510 Interferon beta 1 …
Tumor necrosis factor (ligand) superfamily, member 9 1.4 2.1 NM_010510 Interferon beta 1 …
[PDF][PDF] Advances in Toll-like receptor signaling
The Toll-like receptor 4 (TLR4) was originally known as the lipopolysaccharide (LPS)
signaling receptor but, as discoveries unfolded, the enormous amount of information …
signaling receptor but, as discoveries unfolded, the enormous amount of information …