Venous thrombosis is a leading cause of morbidity and mortality in industrialized countries,
especially in the elderly. Many risk factors have been identified for venous thrombosis that …

Abstract Coagulation factor XII (FXII, Hageman factor, EC= 3.4. 21.38) is the zymogen of the
serine protease, factor XIIa (FXIIa). FXII is converted to FXIIa through autoactivation induced …

For a long time, blood coagulation and innate immunity have been viewed as interrelated
responses. Recently, the presence of leukocytes at the sites of vessel injury has been …

Leukocyte-derived microparticles (LMPs) may originate from neutrophils, monocytes/
macrophages, and lymphocytes. They express markers from their parental cells and harbor …

Hypercholesterolemia is a major risk factor for atherosclerosis. It also is associated with
platelet hyperactivity, which increases morbidity and mortality from cardiovascular disease …

This review discusses the role of microparticles in inflammation, coagulation, vascular
function, and most importantly, their physiological and pathological functions in sepsis …

Fractalkine (CX3CL1, FKN) is expressed in the inflamed vascular wall and absence of FKN
reduces atherogenesis. Whether FKN is expressed throughout all stages of atherosclerotic …

Endotoxin (lipopolysaccharide, LPS) produced by gram-negative bacteria initiates a host of
pro-inflammatory effects through Toll-like receptor 4 (TLR-4). We reported previously that …

[Frontiers in Bioscience E4, 289-299, January 1, 2012] 289 Tissue factor in blood cells and
endothelial cells Bjarne Osterud1, 2 Page 1 [Frontiers in Bioscience E4, 289-299, January 1 …

Background Circulating endothelial cells and microparticles have prognostic value in
cancer, and might be predictors of response to chemotherapy and antiangiogenic …