Histone acetylation via CBP/p300 coordinates the expression of proinflammatory cytokines
in the activation phase of inflammation, particularly through mitogen-activated protein …

During mammalian development, cardiac specification and ultimately lineage commitment to
a specific cardiac cell type is accomplished by the action of specific transcription factors …

Background Long-term acetate supplementation reduces neuroglial activation and
cholinergic cell loss in a rat model of lipopolysaccharide-induced neuroinflammation …

Protein lysine acetylation plays an important role in the normal functioning of cells, including
gene expression regulation, protein stability and metabolism regulation. Although large …

Lysine acetylation is a well-studied post-translational modification on both histone and
nonhistone proteins. More than 2000 acetylated proteins and 4000 lysine acetylation sites …

Acetylation of lysine residues is an important posttranslational modification found in all
domains of life. α-tubulin is specifically acetylated on lysine 40, a modification that serves to …

The phosphoglycerate kinase-2 (Pgk2) gene is regulated in a tissue-, cell type-, and
developmental stage-specific manner during spermatogenesis and is required for normal …

In the past ten years the number of acetylated proteins reported in literature grew
exponentially. Several authors have proposed that acetylation might be a key component in …

Lysine acetylation is a protein post-translational modification (PTM) initially discovered in
abundant proteins such as tubulin, whose acetylated form confers microtubule stability, and …

Smad family proteins are essential intracellular mediators that regulate transforming growth
factor-β (TGF-β) ligand signaling. In response to diverse stimuli, Smad7 is rapidly expressed …