Investigations on the 4‐Quinolone‐3‐Carboxylic Acid Motif Part 5: Modulation of the Physicochemical Profile of a Set of Potent and Selective Cannabinoid‐2 Receptor …
C Mugnaini, S Nocerino, V Pedani, S Pasquini… - …, 2012 - Wiley Online Library
Three heterocyclic systems were selected as potential bioisosteres of the amide linker for a
series of 1, 6‐disubstituted‐4‐quinolone‐3‐carboxamides, which are potent and selective …
series of 1, 6‐disubstituted‐4‐quinolone‐3‐carboxamides, which are potent and selective …
A supermolecular curcumin for enhanced antiproliferative and proapoptotic activities: molecular characteristics, computer modeling and in vivo pharmacokinetics
Q Tan, J Wu, Y Li, H Mei, C Zhao, J Zhang - Nanotechnology, 2012 - iopscience.iop.org
The supermolecular curcumin (SMCCM) exhibiting remarkably improved solubility and
release characteristics was fabricated to increase the oral bioavailability in rat as well as the …
release characteristics was fabricated to increase the oral bioavailability in rat as well as the …
A combined targeted/phenotypic approach for the identification of new antiangiogenics agents active on a zebrafish model: from in silico screening to cyclodextrin …
A combined targeted/phenotypic approach for the rapid identification of novel
antiangiogenics with in vivo efficacy is herein reported. Considering the important role …
antiangiogenics with in vivo efficacy is herein reported. Considering the important role …