Folate plays a critical role in the prevention of uracil incorporation into DNA and
hypomethylation of DNA. This activity is compromised when vitamin B12 concentration is …

Micronucleus (MN) is a small additional nucleus and is readily identifiable by light
microscopy. Biologically, micronuclei are the chromosome fragments or whole …

A global methodology, called Foodomics, which allows carrying out a comprehensive
evaluation of the health benefits of food ingredients is presented in this work. The new …

Through its involvement in over 400 NAD (P)-dependent reactions, niacin status has the
potential to influence every area of metabolism. Niacin deficiency has been linked to …

Chromosomal instability (CIN) is an important hallmark to oncogenesis and can be
diagnosed morphologically by the presence of nuclear anomalies such as micronuclei (MN) …

Cellular phenotypes can be applied as biomarkers to differentiate normal from abnormal
biological conditions. Several cytogenetic methods have been developed and allow the …

Thyroid hormones are recognized as the key metabolic hormones that play a critical role in
the development of central nervous system (CNS) throughout life. The present study was …

Resveratrol found in fruits, vegetables and beverages such as red wine, has been
extensively evaluated for its anticardiovascular disease and cancer preventive effects. Even …

Biotin serves as a covalently bound coenzyme in five human carboxylases; biotin is also
attached to histones H2A, H3, and H4, although the abundance of biotinylated histones is …

Thyroid hormones are recognized as key metabolic hormones that play a critical role in the
central nervous system development throughout life. In the present study, we studied the …