Testing the hypothesis that diphtheria–tetanus–pertussis vaccine has negative non-specific and sex-differential effects on child survival in high-mortality countries

P Aaby, C Benn, J Nielsen, IM Lisse, A Rodrigues… - BMJ open, 2012 - bmjopen.bmj.com
Background Measles vaccines (MV) have sex-differential effects on mortality not explained
by protection against measles infection. Objective The authors examined whether whole-cell …

Non-specific and sex-differential effects of vaccinations on child survival in rural western India

S Hirve, A Bavdekar, S Juvekar, CS Benn, J Nielsen… - Vaccine, 2012 - Elsevier
BACKGROUND: Studies from Africa have suggested marked non-specific effects (NSEs) of
routine vaccinations with effects on child survival. There have been few studies from Asia …

Saving lives by training innate immunity with bacille Calmette-Guerin vaccine

P Aaby, CS Benn - Proceedings of the National Academy of …, 2012 - National Acad Sciences
For many years, public health practitioners have been puzzled by the fact that vaccines
developed to fight specific diseases also have nonspecific effects that alter the host …

Vaccine programmes must consider their effect on general resistance

P Aaby, H Whittle, CS Benn - BMJ, 2012 - bmj.com
Recent randomised trials have shown that live vaccines such as measles and BCG enhance
general resistance, preventing other infections as well as the target infection. However …

Commentary: BCG vaccination halves neonatal mortality

F Shann - The Pediatric infectious disease journal, 2012 - journals.lww.com
There is now strong evidence that vaccines have very substantial nonspecific (heterologous)
effects in children in high-mortality regions. 1, 2 The hypothesis states that, until the next …

No effect of oral polio vaccine administered at birth on mortality and immune response to BCG. A natural experiment

N Lund, A Andersen, I Monteiro, P Aaby, CS Benn - Vaccine, 2012 - Elsevier
BACKGROUND: WHO recommends oral polio vaccine at birth (OPV0) in polio endemic
countries. During a period without OPV in Guinea-Bissau in 2004, we observed that not …

No evidence of bias in trial showing BCG reduces neonatal mortality

P Aaby, A Roth, S Biering-Sørensen… - Journal of Infectious …, 2012 - academic.oup.com
To the Editor—We would like to comment on the data presented by Aaby et al regarding
their randomized trial of BCG in low-birth-weight children [1]. The authors designed their trial …

[引用][C] Why vaccine programmes can no longer ignore non-specific effects

P Aaby, H Whittle… - BMJ (Overseas and …, 2012 - pascal-francis.inist.fr
Why vaccine programmes can no longer ignore non-specific effects CNRS Inist Pascal-Francis
CNRS Pascal and Francis Bibliographic Databases Simple search Advanced search Search by …

[引用][C] Australia, immunisation, GAVI, and the non‐specific effects of vaccines

F Shann - Australian and New Zealand Journal of Public Health, 2012 - Wiley Online Library
14. Riley ID, Tarr PI, Andrews M, et al. Immunisation with a polyvalent pneumococcal
vaccine. Reduction of adult respiratory mortality in a New Guinea highlands community …