Stromal control of cystine metabolism promotes cancer cell survival in chronic lymphocytic leukaemia

W Zhang, D Trachootham, J Liu, G Chen… - Nature cell …, 2012 - nature.com
Tissue stromal cells interact with leukaemia cells and profoundly affect their viability and
drug sensitivity. Here we show a biochemical mechanism by which bone marrow stromal …

Prognostic significance of del 17p, ZAP-70 and CD38 as independent indicators for B-CLL: correlation to response to treatment and disease outcome

NS El-Kinawy, HM Sharaf, MA El-Hamid - Egyptian Journal of Medical …, 2012 - ajol.info
Prognostic markers as CD38 and ZAP-70 and specific chromosomal abnormalities as del
17p have now been developed to refine the risk of progressive disease in chronic …

Present status and perspectives in functional analysis of p53 in chronic lymphocytic leukemia

E De Viron, L Michaux, N Put, F Bontemps… - Leukemia & …, 2012 - Taylor & Francis
Aberrations of TP53 (mutations and/or deletions) are associated with a dismal prognosis in
chronic lymphocytic leukemia (CLL). Complete loss of ATM is another mechanism of failed …

Present and future application of nanoparticle based therapies in B-chronic lymphocytic leukemia (B-CLL)

E Mansilla, GH Marin, L Núñez, G Larsen… - Chronic Lymphocytic …, 2012 - books.google.com
We describe a variety of polymer biodegradable nanoparticles (BNPs) that can be created in
an attempt to find an effective and durable treatment for B-Chronic Lymphocytic Leukemia (B …