Abstract Interleukin-1 (IL-1) is a highly active pro-inflammatory cytokine that lowers pain
thresholds and damages tissues. Monotherapy blocking IL-1 activity in autoinflammatory …

Low-grade inflammation is a common feature in subjects with type 2 diabetes (T2D). Heart
disease, the metabolic syndrome and T2D all have in common the increased concentration …

Background—To test formally the inflammatory hypothesis of atherothrombosis, an agent is
needed that reduces inflammatory biomarkers such as C-reactive protein, interleukin-6, and …

Background Everolimus-eluting stent (EES) reduces the risk of restenosis in elective
percutaneous coronary intervention. However, the use of drug-eluting stent in patients with …

Abstract IL-17A (IL-17) is the signature cytokine produced by Th17 cells and has been
implicated in host defense against infection and the pathophysiology of autoimmunity and …

One of the major therapeutic challenges in the arena of interventional cardiology is to design
strategies aimed at reducing myocardial tissue damage after myocardial infarction. In …

In the United States alone, 400 000 Americans die annu-ally of coronary artery disease, and
1 000 000 suffer acute coronary events, ie, myocardial infarction and sudden cardiac death …

Although evidence has linked the consumption of saturated fat (SF) to increased LDL levels
and an increased risk of the development of cardiovascular disease (CVD), recent findings …

Germ cell testicular cancer (TC) represents a malignancy with high cure rates. Since the
introduction of cisplatin-based chemotherapy in the late 1970s, the 5-year survival rate has …

Clinical complications of atherosclerosis arise primarily as a result of luminal obstruction due
to atherosclerotic plaque growth, with inadequate outward vessel remodeling and plaque …