Tick cell lines for study of Crimean-Congo hemorrhagic fever virus and other arboviruses

L Bell-Sakyi, A Kohl, DA Bente… - Vector-Borne and …, 2012 - liebertpub.com
Continuous cell lines derived from many of the vectors of tick-borne arboviruses of medical
and veterinary importance are now available. Their role as tools in arbovirus research to …

Suppression of Arabidopsis ARGONAUTE1-mediated slicing, transgene-induced RNA silencing, and DNA methylation by distinct domains of the Cucumber mosaic …

CG Duan, YY Fang, BJ Zhou, JH Zhao, WN Hou… - The Plant …, 2012 - academic.oup.com
Unique among the known plant and animal viral suppressors of RNA silencing, the 2b
protein interacts directly with both small interfering RNA (siRNA) and ARGONAUTE1 (AGO1) …

Cucumber mosaic virus suppressor 2b binds to AGO4‐related small RNAs and impairs AGO4 activities

S Hamera, X Song, L Su, X Chen, R Fang - The Plant Journal, 2012 - Wiley Online Library
Cucumber mosaic virus suppressor 2b (CMV2b) is a nuclear viral suppressor that interferes
with local and systemic silencing and inhibits AGO1 slicer activity. CMV2b‐mediated …

Viral suppression of RNA silencing

L Jiang, CH Wei, Y Li - Science China Life Sciences, 2012 - Springer
Gene silencing (RNA silencing) plays a fundamental role in antiviral defense in plants, fungi
and invertebrates. Viruses encode proteins that suppress gene silencing to counter host …

RNA-dependent RNA polymerase 6 of rice (Oryza sativa) plays role in host defense against negative-strand RNA virus, Rice stripe virus

L Jiang, D Qian, H Zheng, LY Meng, J Chen, WJ Le… - Virus research, 2012 - Elsevier
RNA-dependent RNA polymerases (RDRs) from fungi, plants and some invertebrate
animals play fundamental roles in antiviral defense. Here, we investigated the role of RDR6 …

Targeting of dicer-2 and RNA by a viral RNA silencing suppressor in Drosophila cells

N Qi, L Zhang, Y Qiu, Z Wang, J Si, Y Liu… - Journal of …, 2012 - Am Soc Microbiol
ABSTRACT RNA interference (RNAi) is a eukaryotic gene-silencing mechanism that
functions in antiviral immunity in diverse organisms. To combat RNAi-mediated immunity …

The VP3 Factor from Viruses of Birnaviridae Family Suppresses RNA Silencing by Binding Both Long and Small RNA Duplexes

A Valli, I Busnadiego, V Maliogka, D Ferrero… - 2012 - journals.plos.org
RNA silencing is directly involved in antiviral defense in a wide variety of eukaryotic
organisms, including plants, fungi, invertebrates, and presumably vertebrate animals. The …

Manipulation of plant host susceptibility: an emerging role for viral movement proteins?

K Amari, F Vazquez, M Heinlein - Frontiers in plant science, 2012 - frontiersin.org
Viruses encode viral suppressors of RNA silencing (VSRs) to counteract RNA silencing, a
major antiviral defense response in plants. Recent studies indicate a role of virus-derived …

RNA silencing as a cellular defense against HIV‐1 infection: progress and issues

VR Sanghvi, LF Steel - The FASEB journal, 2012 - Wiley Online Library
MicroRNAs (miRNAs) are known to have a role in gene regulation that is closely integrated
into the pathways that control virtually all fundamental cell processes of growth …

Even viruses can be beneficial microbes

MJ Roossinck - Microbiology Australia, 2012 - CSIRO Publishing
Although viruses are almost always thought of as pathogens, most viruses probably do not
cause disease, and some provide essential benefits to their hosts. Beneficial viruses are …