Defining the molecular blueprint that drives CD8+ T cell differentiation in response to infection
A cardinal feature of adaptive, cytotoxic T lymphocyte (CTL)-mediated immunity is the ability
of naïve CTLs to undergo a program of differentiation and proliferation upon activation …
of naïve CTLs to undergo a program of differentiation and proliferation upon activation …
Induction of stronger and long lasting vaccine immunity to tuberculosis
P Bakhru - 2012 - digitalcommons.library.tmc.edu
Tuberculosis is a major cause of death due to an infection in mankind. BCG vaccine protects
against childhood tuberculosis although, it fails to protect against adult tuberculosis. BCG …
against childhood tuberculosis although, it fails to protect against adult tuberculosis. BCG …
Cytotoxic T-Cells in HIV-1:" The Good" and" The Bad"
JM Glanville - 2012 - ora.ox.ac.uk
CD8+ T-cell antigen sensitivity is critical for optimal control of persistent viral infections,
including HIV-1. The devastating HIV-1 pandemic may be countered by development of a …
including HIV-1. The devastating HIV-1 pandemic may be countered by development of a …
[PDF][PDF] Emergence and fate of stem cell-like Tcf7+ CD8+ T cells during a primary immune
JG Silva, DP Ferreira, A Dumez, T Wyss - differentiation, 2012 - serval.unil.ch
In response to infection, naïve CD8+ T cells (TN) yield a large pool of short-lived terminal
effector (TTE) cells that eliminate infected host cells. In parallel, a minor population of stem …
effector (TTE) cells that eliminate infected host cells. In parallel, a minor population of stem …
The transcriptional regulation of CD8⁺ T cells during acute infection
JA Best - 2012 - escholarship.org
CD8⁺ T cells posses the dual function of specifically targeting and killing host cells
harboring intracellular pathogens, while at the same time maintaining the ability to" …
harboring intracellular pathogens, while at the same time maintaining the ability to" …