Stimulation of dopamine receptor D5 expressed on dendritic cells potentiates Th17-mediated immunity

C Prado, F Contreras, H González, P Díaz… - The Journal of …, 2012 - journals.aai.org
Dendritic cells (DCs) are responsible for priming T cells and for promoting their
differentiation from naive T cells into appropriate effector cells. Emerging evidence suggests …

Endothelial cells are able to synthesize and release catecholamines both in vitro and in vivo

D Sorriento, G Santulli, C Del Giudice, A Anastasio… - …, 2012 - Am Heart Assoc
Recently it has been demonstrated that catecholamines are produced and used by
macrophages and mediate immune response. The aim of this study is to verify whether …

Mind over cytokines: Crosstalk and regulation between the neuroendocrine and immune systems

S Miyake - Clinical and Experimental Neuroimmunology, 2012 - Wiley Online Library
Crosstalk between the neuroendocrine and immune systems is essential for the
maintenance of homeostasis in our bodies. Recent advances in neuroscience and …

[HTML][HTML] Characterization and function of the human macrophage dopaminergic system: implications for CNS disease and drug abuse

PJ Gaskill, L Carvallo, EA Eugenin… - Journal of …, 2012 - Springer
Background Perivascular macrophages and microglia are critical to CNS function. Drugs of
abuse increase extracellular dopamine in the CNS, exposing these cells to elevated levels …

Role of peripheral and brain-derived dopamine (DA) in immune regulation

BE Tóth, M Vecsernyés, T Zelles… - Advances in …, 2012 - content.iospress.com
There is a well-defined influence of dopamine (DA) within the immune system. It can be
synthesized not only in neurons, but also in immune cells, especially in T cells. In addition …

First appearance and location of catecholaminergic cells during experimental arthritis and elimination by chemical sympathectomy

S Capellino, K Weber, M Gelder, P Härle… - Arthritis & …, 2012 - Wiley Online Library
Objective The sympathetic nervous system is proinflammatory in early collagen‐induced
arthritis (CIA) and antiinflammatory in late disease. In late arthritis, sympathetic innervation of …

Dopaminergic Modulation of CD4+CD25high Regulatory T Lymphocytes in Multiple Sclerosis Patients during Interferon-β Therapy

M Cosentino, M Zaffaroni, M Trojano, M Giorelli… - …, 2012 - karger.com
Objective: We investigated dopaminergic inhibition of CD4+ CD25high regulatory T
lymphocytes (Treg) in relapsing-remitting multiple sclerosis (MS) patients treated with …

Dopamine in the immune system: dopamine receptors in immune cells, potent effects, endogenous production and involvement in immune and neuropsychiatric …

M Levite - … Immunity: Neurotransmitters and Neuropeptides in the …, 2012 - Springer
Dopamine is undoubtedly produced in many, if not all, types of immune cells, and under
certain conditions can be released to the extracellular milieu by these cells, resulting in …

Cells, molecules and mechanisms involved in the neuro-immune interaction

R Pacheco, F Contreras, C Prado - Cell Interact, 2012 - books.google.com
The existence of a surveillance and protection system against pathogens and malignant
cells has evolved until reach, in the most complex organisms, a very sophisticated immune …

Expression profile of genes associated with the dopamine pathway in vitiligo skin biopsies and blood sera

E Reimann, K Kingo, M Karelson, P Reemann, U Loite… - Dermatology, 2012 - karger.com
Background: Dopamine has been proven to be toxic for melanocytes. In vitiligo patients the
level of dopamine is increased and the functioning of several enzymes participating in the …